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R. Eugene Ramsay, M.D.

International Center for Epilepsy
Ochsner Medical Center
1514 Jefferson Highway
7th Floor, Clinic Tower
New Orleans, LA 70121
504-842-3980
E-mail:
eramsay@epiworld.com

Higher Education

1959-63 B.S., Physics, University of Florida, Gainesville, FL
1965-69 M.D., University of Florida, Gainesville, FL

Certifications

1977 American Board of Qualification in Electroencephalography
1978 American Board of Psychiatry & Neurology

Postgraduate Training

1969-70 Intern, Department of Surgery, Shands Teaching Hospital, University of Florida, Gainesville, FL

1970-71 Clinical Fellowship, Department of Neurology, Shands Teaching Hospital, University of Florida, Gainesville, FL

1973-75 Clinical Fellowship, Department of Neurology, Shands Teaching Hospital, University of Florida, Gainesville, FL

1975-76 Fellow in Epilepsy and Electroencephalography, Department of Neurology Veterans Administration Medical Center, Gainesville, FL; Mentor - B.J. Wilder, M.D.Faculty Appointments

1977-78 Assistant Professor, Department of Neurology, Director EEG Laboratory and EEG Technologist training program, LSU School of Medicine, Shreveport, LA

1978-83 Assistant Professor, Department of Neurology, Director of Epilepsy Services, University of Miami School of Medicine; Staff Neurologist and Director of Clinical Neurophysiology Laboratory, Veterans Affairs Medical Center, Miami, FL

1978-79 Acting Director, EEG Laboratory, Jackson Memorial Hospital, Miami, FL

1983-90 Associate Professor, Department of Neurology, Director of Comprehensive Epilepsy Center, University of Miami School of Medicine; Staff Neurologist and Director of Clinical Neurophysiology Laboratory, Veterans Affairs Medical Center, Miami, FL

1990-93 Professor, Department of Neurology, Director of The International Center for Epilepsy, University of Miami School of Medicine; Staff Neurologist and Director of Clinical Neurophysiology Laboratory, Veterans Affairs Medical Center, Miami, FL

1993- Professor, Department of Neurology, Director of The International Center for Epilepsy, University of Miami School of Medicine; Staff Neurologist and Director of Clinical Neurophysiology Laboratory, Veterans Affairs Medical Center; Director, EEG Laboratory, Jackson Memorial Hospital, Miami, FL

Publications

Books and Monographs Published:

1. Wilder BJ and Ramsay RE. Anticonvulsant Drugs - Epilepsy and its Treatment in: American Academy of Neurology Review Book, American Academy of Neurology, Publishers, Minneapolis, Minnesota, June 1976.

2. Willmore LJ, Wilder BJ and Ramsay RE. Episodic Loss of Consciousness: Syncope, Seizures and Narcolepsy. Clinical Concept of Neurological Disorders. Edited by LE Cluff and JE Johnson, JF Toole, guest editor; William and Wilkins Co., Baltimore, 141-154, 1977.

3. Ramsay RE. Epilepsy in Pregnancy. Proceeds of the Epilepsy International Symposium. Editor, Juan Wada, M.D., Sept. 1978.

4. Ramsay RE. Electrophysiological Recording in the ICU. Intensive Care for Neurological Trauma and Disease, Academic Press, Inc., New York, Eds. Green, Marshall and Gallagher, 1982.

5. Tsubokawa T and Ramsay RE. Evoked Responses: Methodology and Clinical Application in Neurological Intensive Care Unit. Intensive Care for Neurological Trauma and Disease, Academic Press, Inc., New York, Eds. Green, Marshall, and Gallagher, 177-200, 1982.

6. Wong PKH and Ramsay RE. Comparison of Electrophysiologic and Metabolic Changes in the Human Epileptic Cortex, in Brain Ischemia: Quantitative EEG and Imaging Techniques, Progress in Brain Research, Elsevier Science; 62:303-313, 1984.

7. Ramsay RE. Use of Phenytoin and Carbamazepine in Treatment of Epilepsy. Neurologic Clinics Epilepsy, Eds. Porter and Theodore, W.B. Saunders Company, Pennsylvania, 4(3):585 600, Aug. 1986.

8. Ramsay RE and Sanchez RM. Antiepileptic Drugs, Pregnancy, and Breast Feeding. Merritt Putnam Quarterly 3(2), Aug. 1986.

9. Wu FY, Slater JD, Ramsay RE and Honig LS. Neural Networks 10. Ramsay RE and Curtis VL. Epilepsy, the Adolescent Female, and Pregnancy in: Handbook of Pediatric Epilepsy. Edited by J. V. Murphy and F. Dehkharghani, Marcel Dekker, Inc., New York, 307-340, 1992.

11. Ramsay RE. Acute Treatment of Seizures in: Emergent and Urgent Neurology. Edited by W.M. Weiner, J.B. Lippincott Company, Pennsylvania, 109-133, 1992.

12. Ramsay RE and Slater JD. Bromides in: The Treatment of Epilepsy: Principles and Practice. Edited by E. Wyllie, Lea & Febiger, Pennsylvania, 955-958, 1993.

13. Ramsay RE, Cohen A and Brown MC. Coexisting Epilepsy and Non-Epileptic Seizures in: Non-Epileptic Seizures. Edited by A. J. Rowan and J.R. Gates, Butterworth-Heinemann, Massachusetts, 47-54, 1993.

14. Fisher RS, Uthman BM, Ramsay RE, Morrell F, Penry JK, Velasco F, Wilder BJ, Whistler WW, Krauss GL and Davis R. Alternate Surgical Techniques for Epilepsy in: Surgical Treatment of the Epilepsies, Second Edition, edited by J. Engel, Jr. Raven Press, Ltd., New York, 549-556, 1993.

15. Ramsay RE and Slater JD. Antiepileptic Drugs in Clinical Development. In: New antiepileptic drug development: Preclinical and clinical aspects. Eds JA French & MA Dichter. Epilepsy Research, (Suppl 10) 45-67, 1993. Elsevier Science Pubishlers B V, Amsterdam

16. Ramsay, RE. Gabapentin: Toxicity. Antiepileptic Drugs, Fourth Edition, edited by R. H. Levy, R. H. Mattson, and B. S. Meldrum. Raven Press, Ltd., New York, 857-860, 1995.

17. Ramsay, RE. DeToledo, J. Gabapentin and Felbamate in: Porter RJ, Chadwick D (eds). The Epilepsies 2. Butterworth-Heinemann, 1997, 223-246.

18. DeToledo, J and Ramsay, RE. Clinical stimulations in the Diagnosis and Management of Epilepsy. Norwalk. Medical Age Publishing, 1997, 1-18

19. Ramsay, RE. and Detoledo, J. Acetazolamide. Epilepsy: A comprehensive textbook, edited by J. Engle and T. A. Pedley. Lippincott-Raven Publishers, Philadelphia, 1-7, 1997


Referred journal articles and exhibitions:

1. Serrano EE, Roye DB, Hammer RH and Wilder BJ. Plasma Diphenylhydantoin Values After Oral and Intramuscular Administration of Diphenylhydantoin. Neurology, 23:311-317, 1973.

2. Wilder BJ, Serrano EE and Ramsay RE. Plasma Diphenylhydantoin Levels After Loading and Maintenance Doses, Clin Pharm Ther 14:797-801, 1973.

3. Wilder BJ, Serrano EE, Ramsay RE and Buchanan R. A Method for Shifting from Oral to Intramuscular Diphenylhydantoin Administration, Clin Pharm Ther, 16:507-513, 1974.

4. Wilder BJ and Ramsay RE. Psychological Aberrations Associated with Antiepileptic Drugs, Clin EEG, 5(4):199-200, 1974.

5. Cereghino JJ, Wilder BJ, Kupferberg HJ, Yonekawa WD, Perchalski RJ, Ramsay RE, White BG, Penry JK and Smith LD. A Single Dose Study of Mexiletine (KO1173), Epilepsia, 16:665 672, 1975.

6. Muniz C, Forman AJ, Wilder BJ and Ramsay RE. Lithium Toxicity with Low Serum Levels, Clin EEG, 7:31-34, 1976.

7. Wilder BJ and Ramsay RE. Oral and Intramuscular Phenytoin, Clin Pharm Ther, 19:360-364, 1976.

8. Wilder BJ, Ramsay RE, Willmore LJ, Feussner GF, Perchalski RJ and Shumate JB. Efficacy of Intravenous Phenytoin in the Treatment of Status Epilepticus: Kinetics of Central Nervous System Penetration, Ann Neurol, 1:511-518, 1977.

9. Ramsay RE, Strauss RG, Wilder BJ and Willmore LJ. Status Epilepticus in Pregnancy: Effect of Phenytoin Malabsorption on Seizure Control, Neurol, 28:85-89, 1978.

10. Strauss RG, Ramsay RE, Willmore LJ and Wilder BJ. Hematologic Effects of Phenytoin Therapy During Pregnancy, OB GYN, 51:682-685, 1978.

11. Willmore LJ, Wilder BJ, Ramsay RE, Mayersdorf A and Sypert GW. Identification of Speech Lateralization by Intracarotid Injection of Methohexital, Ann Neurol, 4:232-235, 1978.

12. Ramsay RE, Hammond EJ, Perchalski RJ and Wilder BJ. Brain Uptake of Phenytoin, Phenobarbital, and Diazepam, Arch Neurol, 36:535-539, 1979.

13. Strauss RA, Ramsay RE, Willmore LJ, Spellacy WM and Wilder BJ. Epilepsy and Pregnancy: Serum Thyroxine Levels During Phenytoin Therapy, OB Gyn, 53(3):344-347, 1979.

14. Hammond EJ, Ramsay RE, Villareal HJ and Wilder BJ. Effects of Intracortical Injection of Blood and Blood Components on the Electrocorticogram, Epilepsia, 21:3-14, 1980.

15. Ramsay RE and Herskowitz A. Usefulness of 24 hour Ambulatory EEG in the Evaluation of the Neurological Patient, ISAM-GENT, 234-243, 1981.

16. Monaco F, Ramsay RE and Vazquez D. Anticonvulsant Drugs Determined by EMIT in Spiked Brain Samples: A Correlation with HPLC Values, Epilepsia, 23:15-18, 1982.

17. Monaco F, Mutani R, Piredda S, Traccis S and Ramsay RE. Brain Uptake of Carbamazepine in the Cat, Epilepsia, 23:19-22, 1982.

18. Goldberg RN, Goldman SL, Ramsay RE and Feller R. Detection of Seizure Activity in the Paralyzed Neonate Using Continuous Monitoring, Pediatrics, 69:583-586, 1982.

19. Wheeler SD, Ramsay RE and Weiss J. Drug Induced Down Beat Nystagmus, Ann Neurol, 12:227-228, 1982.

20. Leppik IE, Derivan AT, Homan RW, Walker J, Ramsay RE and Patrick B. Double-blind Study of Lorazepam and Diazepam in Status Epilepticus, JAMA, 249:1452-1454, 1983.

21. Ramsay RE, Wilder BJ, Berger JR and Bruni J. A Double-blind Study Comparing Carbamazepine with Phenytoin as Initial Seizure Therapy in Adults, Neurology, 33:904-910, 1983.

22. Curless RG, Holtzman BH and Ramsay RE. Paraldehyde Therapy in Childhood Status Epilepticus, Arch Neurol, 40:477-480, 1983.

23. Ramsay RE. Safe Readministration of Valproate After an Episode of Hepatotoxicity, Ann Neurol, 13:688, 1983.

24. Wilder BJ, Ramsay RE, Murphy JV, Karas BJ, Marquardt K and Hammond EJ. Comparison of Valproic Acid and Phenytoin in Newly Diagnosed Tonic-Clonic Seizures, Neurology, 33:1474-1476, 1983.

25. Ramsay RE, Van Buren J, Sick T, Rosenthal M and Kreisman N. Oxygen Sufficiency During Seizures and in Human Epileptic Foci, Advances in Epileptology, XVth Epil Int Symp, 105-110, 1984.

26. Ramsay RE, Perchalski RJ, Resillez M and Cohen H. Changes in Hormone Levels and Anticonvulsant Metabolism During Pregnancy, Advances in Epileptology, XVth Epil, Int Symp, 233-237, 1984.

27. Ramsay, RE. Controlled and Comparative Trials with Valproate: United States. Epilepsia, 25(Suppl 1):S40-S43, 1984.

28. Ramsay, RE. Effect of Hormones on Seizure Activity During Pregnancy. J Clin Neurophys, 4:23-25, 1987.

29. Ramsay, RE. Pharmacokinetics and Clinical Use of Parenteral Phenytoin, Phenobarbital, and Paraldehyde. Epilepsia, 30(Suppl 2):S1-S3, 1989.

30. Curless RG, Ramsay RE, Katz DA, Gadia CA and Sheehan KA. Ambulatory EEG Recordings in Children with Infrequent Seizures. Ped Neurol, 6:184-185, 1990.

31. Ramsay RE, McManus D, Guterman A, Briggle TV, Vazquez D, Perchalski R, Yost RA and Wong P. Carbamazepine Metabolism in Humans: Effect of Concurrent Anticonvulsant Therapy. Ther Drug Monitoring, 12:235-241, 1990.

32. Mellman TA, Ramsay RE and Fitzgerald SG. Divergence of PTSD and Narcolepsy Associated with Military Trauma. J of Anxiety Disorders, 5:267-272, 1991.

33. Ramsay RE and Slater JD. Effects of Antiepileptic Drugs on Hormones. Epilepsia, 32(Suppl 6):S60-S67, 1991.

34. Ramsay RE, Pellock JM, Garnett WR, Sanchez RM, Valakas AM, Wargin WA, Lai AA, Hubbell J, Chern WH, Allsup T and Otto V. Pharmacokinetics and Safety of Lamotrigine (Lamictal) in Patients with Epilepsy. Epilepsy Research, 10:191-200, 1991.
35. Brown MC, Levin BE, Ramsay RE, Duchowny MS and Katz D. Characteristics of Patients with Non-epileptic Seizures. J Epilepsy, 4:225-229, 1991.

36. Honig LS, Ramsay RE and Sheremata WA. Event-Related Potential P300 in Multiple Sclerosis: Relation to Magnetic Resonance Imaging and Cognitive Impairment. Arch Neurol, 49:44-50, 1992.

37. Ramsay RE, Wilder BJ, Murphy JV, Holmes GL, Uthman B, Slater JD, Morris DD, Shu VS and Pierce MW. Efficacy and Safety of Valproic Acid Versus Phenytoin as Sole Therapy for Newly Diagnosed Primary Generalized Tonic-Clonic Seizures. J Epilepsy, 5:55-60, 1992.

38. Landy, HJ, Ramsay RE, Ajmone-Marsan C, Levin BE, Brown MC, Pasarin G and Quencer RM. Temporal Lobectomy for Seizures Associated with Unilateral Schizencephaly. Surg Neurol, 37:477-81, 1992.

39. Mattson RH, Cramer JA, Collins JF, McCutchen CB, Mamdani MB, Davenport J, Lubozynski MF, Ramsay RE, et al. A Comparison of Valproate with Carbamazepine for the Treatment of Complex Partial Seizures and Secondarily Generalized Tonic-Clonic Seizures in Adults. NEJM, 327:765-71, 1992.

40. Landy HJ, Ramsay RE, Slater JD, Casiano RR and Morgan R. Vagus Nerve Stimulation for Complex Partial Seizures: Surgical Technique, Safety, and Efficacy. J Neurosurg, 78:26-31, 1993.

41. Landy HJ, Curless RG, Ramsay RE, Slater J, Ajmone-Marsan C and Quencer RM. Corpus Callosotomy for Seizures Associated with Band Heterotopia. Epilepsia, 34:79-83, 1993.

42. Faught E, Sachdeo RC, Remler MP, Chayasirisobhon S, Iragui-Madoz VJ, Ramsay RE, Sutula TP, Kanner A, Kramer LD, Kamin M and Rosenberg A. Felbamate Monotherapy for Partial Onset Seizures: An Active-Control Trial. Neurology, 43:688-692, 1993.

43. Brown MC, Levin BE, Ramsay RE and Landy HJ. Comprehensive Evaluation of Left Hemisphere Type I Schizencephaly. Arch Neurology, 50:667-669, 1993.

44. Wu FY, Slater JD, Honig LS and Ramsay RE. A Neural Network Design for Event-Related Potential Diagnosis. Comput Biol Med, 23:251-264, 1993.

45. Uthman BM, Wilder BJ, Penry JK, Dean C, Ramsay RE, Reid SA, Hammond EJ, Tarver WB and Wernicke JF. Treatment of Epilepsy by Stimulation of the Vagus Nerve. Neurology, 43:1338-1345, 1993.

46. Wu FY, Slater JD, Ramsay RE and Honig LS. Feature Extraction of Event-Related Potential Waveforms by Neural Networks, IEEE, 1532-1537, 1993.

47. Slater JD, Wu FY, Honig LS, Ramsay RE and Morgan R. Neural Network Analysis of the P300 Event-Related Potential in Multiple Sclerosis. Electroencephalography and Clinical Neurophysiology, 90:114-122, 1994.

48. Messenheimer J, Ramsay RE, Willmore LJ, Leroy JR, Zielinski J, Mattson R, Pellock JM, Valakas AM, Womble G, Risner M. Lamotrigine Therapy for Partial Seizures: A Multicenter, Double-blind, Crossover Trial. Epilepsia 35(1): 113-121, 1994 Jan-Feb.

49. Ramsay, RE. Clinical Efficacy and Safety of Gabapentin. Neurology, 44(Suppl 5):S23-S30, 1994.

50. Ramsay RE. Advances in Pharmacotherapy of Epilepsy. Epilepsia, 34(Suppl 5):S9-S16, 1994.

51. The US Gabapentin Study Group: RE Ramsay, et al. The Long-term Safety and Efficacy of Gabapentin (Neurontin7) as Add-on Therapy in Drug-resistant Partial Epilepsy. Epilepsy Research, 18:67-73, 1994.

52. Ben-Menachem E, Manon-Espaillat, Ristanovic R, Wilder BJ, Stefan H, Mirza W, Tarver WB, Wernicke JF and First International Vagus Nerve Stimulation Study Group: RE Ramsay, et al. Vagus Nerve Stimulation for Treatment of Partial Seizures: 1. A Controlled Study of Effect on Seizures. Epilepsia, 35:616-626, 1994.

53. Ramsay RE, Uthman B, Aug.insson L, Upton ARM, Naritoku DK, Willis JK, Treig T, Barolat G, Wernicke JF and the First International Vagus Nerve Stimulation Study Group. Vagus Nerve Stimulation for Treatment of Partial Seizures: 2. Safety, Side Effects and Tolerability. Epilepsia, 35:627-636, 1994.

54. George R, Salinsky M, Kuzniecky R, Rosenfeld W, Bergen D, Tarver WB, Wernicke JF and First International Vagus Nerve Stimulation Study Group: RE Ramsay, et al. Vagus Nerve Stimulation for Treatment of Partial Seizures: 3. Long-Term Follow-Up on First 67 Patients Exiting a Controlled Study. Epilepsia, 35:637-643, 1994.

55. The Vagus Nerve Stimulation Study Group; Ramsay, RE. A Randomized Controlled Trial of Chronic Vagus Nerve Stimulation for Treatment of Medically Intractable Seizures. Neurology, 45:224-230, 1995.

56. Slater JD, Brown MC, Jacobs W and Ramsay RE. Induction of Pseudoseizures Using Intravenous Saline Placebo. Epilepsia, 36(Suppl 6):580-585, 1995.

57. McLean MJ, Ramsay RE, Leppik IE, Rowan AJ, Shellenberger MK, Wallace J, for US Gabapentin Study Group No. 5. Gabapentin as Add-on Therapy in Refractory Partial Epilepsy: A Double-Blind, Placebo-Controlled, Parallel-Group Study. Neurology, 43:2292-2298, 1993.

58. RE Ramsay (corresponding author) for The Tegretol OROS7 Osmotic Release Delivery System Study Group. Double-blind Crossover Comparison of Tegretol7-XR and Tegretol7 in Patients with Epilepsy. Neurology, 45:1703-1706, 1995.

59. Ben-Menachem, Hamberger A, Hedner T, Hammond EJ, Uthman BM, Slater J, Treig T, Stefan H, Ramsay RE, Wernicke JF and Wilder BJ. Effects of Vagus Nerve Stimulation on Amino Acids and Other Metabolites in the CSF of Patients with Partial Seizures. Epilepsy Research. 20: 221-227, 1995.

60. Devinsky O, Leppik I, Willmore LJ, Pellock M, Dean C, Gates J, Ramsay RE and the IV Valproate Study Team. Safety of Intravenous Valproate. Annals of Neurology, 38(4):670-674, 1995.

61. French JA, Mosier M, Walker S, Sommerville K, Sussman N, and the Vigabatrin Protocol 024 Investigative Cohort, Ramsay, RE. A Double-Blind, Placebo-Controlled Study of Vigabatrin 3 g/day in Patients with Uncontrolled Complex Partial Seizures. Neurology. 46(1): 54-61, 1996 Jan

62. Faught E, Wilder BJ, Ramsay RE, Reife RA, Kramer LD, Pledger GW, Karim RM, and the Topiramate YD Study Group. Topiramate Dose-Ranging Trial in Refractory Partial Epilepsy Using 200-, 400-, & 600-mg Daily Dosages. Neurology,46:1684-1690, 1996.

63. Ramsay RE, DeToledo J. Intravenous administration of fosphenytoin: options for the management of seizures. [Review] [12 refs]. Neurology 46(6 Suppl 1):S17-9. 1996;

64. Uthman BM, Wilder BJ, and Ramsay RE. Intramuscular Use of Fosphenytoin: An Overview Neurology, 46(6 Suppl 1): S24-28, 1996.

65. DeToledo, JD, Ramsay RE Marsan, CA. The lunatic and his seizure. Neurology, 47(1):292 293, 1996.

66. DeToledo, JD , Ramsay RE. IM administration of Fosphenytoin. Emergency Medicine. 1996, 26-32.

67. Uthman, Basim M., Wilder, B.J. & Ramsay RE. Intramuscular use of fosphenytoin: an overview. Neurology 46(Suppl 1): S24-8, 1996 Jun

68. Wilder BJ, Campbell K, Ramsay RE, Garnett WR, Pellock JM, Hankin SA, Kugler AR. Safety and tolerance of multiple doses of intramuscularly administered fosphenytoin substituted for oral phenytoin (Dilantin) in epilepsy or neurosurgery patients. Archives of Neurology 53(8): 764-768,1996 Aug

69. DeToledo, JD, Ramsay RE. Patterns of involvement of facial muscles during epileptic and nonepileptic events: review of 654 events. Neurology, 47(3):621-625, 1996 Sep.

70. Nemire Ruth E, Toledo Cindy A, and Ramsay R E. A pharmacokinetic study to determine the Interaction Between valproate and propranolol. Pharmacotherapy 16(6): 1059-1062, 1996 Nov-Dec

71. Mattson,R.H.; Cramer,J.A.; Collins,J.F. Department of Veterans Affairs Epilepsy Cooperative Studies No. 118 and No. 264 Group Ramsay R E. Prognosis for total control of complex partial and secondarily generalized tonic clonic seizures. Neurology, 47 (1): 68-71, 1996

72. DeToledo, J.C., Ramsay, R.E. The mechanism of the ocular autonomic dysfunction during the intracarotid amytal suppression test. Epilepsy Research, 29(): 309-313, 1997

73. Beydoun A, Sackellares JC, Shu V, and The Depakote Monotherapy Partial Study Group, RE Ramsay. Safety and Efficacy of Divalproex Sodium Monotherapy in Partial Epilepsy: A Double-Blind, Concentration-Response Design Clinical Trial. Neurology, 48(1): 182-188, 1997.

74. DeToledo JC, Haddad H, Ramsay, RE. Status epilepticus associated with the combination of valproic acid and clomipramine. Therapeutic Drug Monitoring 19: 71-73, 1997

75. DeToledo JC, Ramsay RE. The mechanism of the ocular autonomic dysfunction during the intracarotid amytal suppression test. Epilepsy Research 26(2): 309-313, 1997

76. Ramsay RE, Uthman B, Leppik IE, Pellock JM, Wilder BJ, Morris D, Cloyd JC. The tolerability and safety of valproate sodium injection given as an intravenous infusion. Journal of Epilepsy 10(1); 1-7, 1997

77. Gallo BV, Slater JD, Toledo C, DeToledo JC, Ramsay RE. Pharmacokinetics and muscle histopathology of intramuscular valproate. Epilepsy Research 28: 11-15; 1997 .

78. DeToledo J, Toledo C, DeCerce, Ramsay RE. Changes in Body Weight with Chronic, High Dose Gabapentin Therapy. Therapeutic Drug Monitoring 19(4): 394-96; 1997 Aug

79. Bergey GK, Morris HH, Rosenfeld W, Blume WT, Penovich PE, Morrell MJ, Lediderman DB, Crockatt JG, LaMoreaux L, Garofalo E, Pierce M, US Gabapentin Study Group 88/89; Ramsay RE. Gabapentin monotherapy: I. an 8-day, double-blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures. Neurology 1997;49:739-745.

80. Ramsay RE, Wilder BJ, Uthman BM, Garnett WR, Pellock JM, Barkley GL, Leppik IE, Knapp LE. Intramuscular fosphenytoin (Cerebyx) in patients requiring a loading dose of phenytoin. Epilepsy Research .28(3): 181-87, 1997

81. Beydoun A, Fischer J, Labar DR, Harden C, Cantrell D, Uthman BM, Sackellares JC, Abou Khalil B, Ramsay RE, Hayes A, Greiner M, Garofalo E, Pierce M, The US Gabapentin Study Group 82/83. Gabapentin monotherapy: II. A 26-week, double-blind, dose-controlled, multicenter study of conversion from polytherapy in outpatients with refractory complex partial or secondarily generalized seizures. Neurology 1997; 49(3): 746-752.

82. Ramsay RE, and DeToledo J. Tonic-Clonic Seizures: A Systematic Review of Antiepilepsy Drug Efficacy and Safety. Clinical Therapeutics 1997; 19(1): 433-

83. DeToledo JC, Minagar A. Lowe MR, Ramsay RE. Skin eruption with gabapentin in a patient with repeated AED induced Stevens Johnson=s syndrome. Submitted to Therapeutic Drug Monitoring, 21: 37-38, 1999.

84. Kriel RL, JC Cloyd, JM Pellock, WG Mitchell, JJ Cereghino, PN Rosman, FE Dreifuss, E Faught, JV Murphy, CY Tsao, K Farrell, AR Riela, R Cheny, GB Sharp, J Farwekk, PK Crumrine, BW Abou-Khalil, AM Chutorian, PP Kotagal, RE Ramsay, DC Bergan, LW Brown, JA Conry, RS Burgeman, RE Kramer, and C Holland. Rectal diazepam gel (Diastat7) in the treatment of Acute Repetitive Seizures. Pediatric Neurology, 20(4), 282-288, 1999

85. Ramsay, R Eugene. Fosphenytoin in the treatment of acute seizures and status epilepticus. Epilepsia, 40(Suppl 6), S73-S82, 1999

86. Mitchell, Wendy G., J. A. conry, P.K. Crumrine, R. L. Kreil, J. J. Cereghino, L. Groves, W. E. Rosenfeld, and the North American Diastat Group, R. Eugene Ramsay. An open-label study of repeated use of diazepam rectal gel (diastat) for episodes of acute breakthrough seizurs and clusters: safety, efficacy and tolerance. Epilepsia, 40 (11), 1611-17, 1999

87. DeToledo JC, Haddad H., Ramsay, RE. Surgical correction of scoliosis in patients with generalized seizures: Risk of vertebral body fracture. Spine. 23:1006-1008, 1997.

88. DeToledo JC, A. Lowe MR, Ramsay RE. Restraining of patients and shoulder dislocations during seizures. Journal of Shoulder & Elbow Surgery. 8:300-2, 1999.

89. DeToledo JC, & Ramsay RE. Fosphenytoin and phenytoin in patients with status epilepticus. Drug Safety 22(6): 459-466, June 2000

90. DeToledo JC, Lowe MR, Griener M, Ramsay RE. Increased seizures after carbamazepine discontinuation: Results from the gabapentin monotherapy trial. In Press, Therapeutic Drug Monitoring Jul 2000.

91. Ramsay RE & Pryor FM. Epilepsy in the elderly. In Press, Neurology 55(Suppl 1):S9-S14, 2000.


Accepted for Publication:
Landy H, Ramsay RE, Ajmone-Marsan C and Slater JD. Incomplete Interhemispheric Fissure and Joint Cingulate Gyrus Interfering with Corpus Callosotomy. J of Neurosurgery. (In press).

Submitted/Under Review:

Finkel Richard S, GB Sharp, Ramsay RE, Riela AR & Rosenfeld SE. The safety of diazepam rectal gel in epileptic patients taking concomitant antiepileptic medication: a multicenter open label study. (Submitted to Archives of Family Medicine).

Ramsay RE Fosphenytoin in the treatment of acute seizures and status epilepticus. (Submitted to J of Epilepsy).

Landy H, Ramsay RE, Bruce J, Slater J, and Ajmone-Marsan C. Surgical Treatment of Seizures Associated with Neuronal Migration Disorders. (Submitted to J of Neurosurgery).

DeToledo JD, Toledo C, Ramsay RE, Rowan AJ, Uthman B, and DeCerce J. Conversion to Lamotrigine Monotherapy: Efficacy and Tolerability of Previous Inducing/Non Inducing AEDs on the Initiation Rates in Patients with Refractory Primary and Secondarily Generalized Seizures

Other works, publications and abstracts:

Feussner FG, Shumate JB, Ramsay RE, Serrano EE and Wilder BJ. The Transfer of Diphenylhydantoin from Plasma to Cerebrospinal Fluid. Epilepsia, 15(2), 1974.

Ramsay RE, Wilder BJ, Strauss R and Willmore LJ. Status Epilepticus During Pregnancy: Effects of Gastrointestinal Malabsorption on Phenytoin Kinetics and Seizures Control. Neurology, 26(2):344, 1976.

Wilder BJ, Ramsay RE, Shumate JB, Feussner FG and Willmore LJ. Therapy of Status Epilepticus with Diphenylhydantoin: Pharmacokinetics and CNS Penetration During IV Infusion. Epilepsia, 17(1), 1976.

Ramsay RE, Wilder BJ, Willmore LJ and Perchalski RJ. Central Nervous System Penetration of Anticonvulsant Drugs. Epilepsia, 18(2):290, 1977.

Willmore LJ, Wilder BJ and Ramsay RE. Effects of Trimethadione and Ethosuximide on Bicuculline Induced Seizures. Epilepsia, 18(2):292, 1977.
Ramsay RE, Strauss R, Wilder BJ, Willmore LJ and Perchalski RJ. Phenytoin Kinetics and Seizure Frequency During Pregnancy, Excerpta Medica, (11th World Congress of Neurology) 130:11-16, Sept. 1977.

Ramsay RE, Willmore LJ, Wilder BJ and Hurd R. Iron-Induced Epileptogenesis: A Physiological Model of Epilepsy. EEG Clin Neurophysiol, 43(4):501, 1977.

Hammond E, Ramsay RE, Villareal H and Wilder BJ. Blood Induced Epileptogenesis: Effect of Various Blood Components. EEG Clin Neurophysiol, 49(1-2):2, 1980.

Ramsay RE, Goldberg MN and Ayyar R. The Effect of Stimulus on the Brain Stem Auditory Evoked Response. EEG Clin Neurophysiol, 49(3-4):76, 1980.
Goldberg R, Feller R, Ramsay RE and Goldman SL. Detection of Seizure Activity in the Paralyzed Neonate. Clin Res, 28:872A, 1980.

Hammond EJ, Wilder BJ, Ramsay RE and Schimpff RD. Immunofluorescent Evidence for a Phenytoin Receptor in the Central Nervous System. Neurology, 30(4):421, 1980.

Ramsay RE, Terrence CF, Resor SR, Harris WA and Coultier G. Cinromide: A Multicenter Open Study of Efficacy and Safety in Epileptic Patients with Uncontrolled Tonic-Clonic Seizures. Epilepsia, 22(2):243, 1981.

Ramsay RE and Herskowitz A. Twenty Four Hour Ambulatory EEG: A Clinical Appraisal. EEG Clin Neurophysiol, 51:20, 1981.

Ramsay RE, Berger JB, Wilder BJ and Bruni J. Carbamazepine vs. Phenytoin in the Initial Treatment of Seizures: A Double-Blind Study. Ann Neurol, 10(1):89, 1981.

Wong PKH and Ramsay RE. Topographic EEG Analysis as a Test of Cortical Function in Cerebral Ischemia. EEG Clin Neurophysiol, 52(3k):114, 1981.

Ramsay RE, Wong PKH and Kelley R. Topographic EEG Changes in Focal Cerebral Lesions. EEG Clin Neurophysiol, 53(3):26, 1982.

Wong PKH and Ramsay RE. Topographic Evoked Potential Changes in Focal Epilepsy. Epilepsia, 24(2):250, 1983.

Guterman A, Vasquez D, Curless RG, Ramsay RE and Wong PKH. Paraldehyde Pharmacokinetics and Its Use in Status Epilepticus. Epilepsia, 24(2):251, 1983.
Ramsay RE, Guterman A, Vasquez D, Perchalski RJ and Wong PKH. Carbamazepine Metabolism in Man: The Effect of Concomitant Anticonvulsant. Epilepsia, 24(2):254, 1983.

Ramsay RE. Valproate Brain Tissue Kinetics Determined by PETT. Neurology, 33(4); Suppl 2:147, 1983.

Leppik IE, Homan RW, Ramsay RE, Patrick B, Dervian AT and Walker JE. Status Epilepticus: A Double Blind Study of Diazepam vs Lorazepam. EEG Clin Neurophysiol, 1983.

Hassel WR, Ginsberg MD, Howard BE, Ramsay RE and Lockwood AH. Measurement of Regional Cerebral Blood Flow (CBF) in Man by In-Vivo Autoradiography and Positron Emission Tomography: Stability, Noise, and Error Considerations. J CBF Metab, 1; Suppl 3:146, 1983.

Guterman A, Ramsay RE and Colten RM. Graphogenic Epilepsy: Report of a 'Scriptogenic' Variant After a Stroke. EEG Clin Neurophysiol, 56:9P, 1983.

Guterman A, Ramsay RE, Wong P and Resillez M. Topographic Changes in Visual Evoked Responses Following a Seizure. EEG Clin Neurophysiol, 56:9P, 1983.

Ramsay RE and Wong P. Topographic EEG analysis: Changes in Focal Lesions with Comparison to PET Scan Findings. EEG Clin Neurophysiol, 57:59P, 1984.

Wong P, Farrell K and Ramsay RE. Spike Mapping: Its Use in Epilepsy. EEG Clin Neurophysiol, 57:59P, 1984.

Guterman A, Wong P, Ramsay RE and Resillez M. Topographic Evoked Potential Changes in Epileptic Patients with Normal Interictal EEGs. EEG Clin Neurophysiol, 58:39P, 1984.

Gregory DL, Wong PK, Farrell K and Ramsay RE. Spike Topography in Benign Rolandic Epilepsy. Epilepsia, 25(5):668, 1984.

Fariello RG, Homan R, Crawford I, Ramsay RE, Guterman A and Krall R. Double-Blind Crossover Study of Progabide in Epilepsy. Epilepsia, 25(5):6733, 1984.

Ramsay RE, Wilder BJ, Sackellares JC, Browne T, Guterman A, Barnes D, Matthews J, Berent S, Donofio BK, Abou-Khalil B and Wagner JG. Multicenter Study on the Efficacy of Zonisamide in the Treatment of Medically Refractory Complex Partial Seizures. Epilepsia, 25(5):673, 1984.

Ramsay RE, Coultier G, Guterman A, Valakas A, Fleck R and Cohen H. Acute Dose Tolerance of Wellbutrin (W) Imipramine (I), and Placebo (P) in Epileptic Patients. Epilepsia, 25(5):661, 1984.

Guterman A, Ramsay RE, Resillez M and Ramirez E. Comparison of 8 Channel, 24-Hour Ambulatory, Routine and Sleep Deprived EEG in Evaluation of Presumed Seizure Disorders. Epilepsia, 25(5):652, 1984.

Marcos J, Ramsay RE, Duchouny M and Wong PKH. Centro-Temporal Spikes in Childhood are Not Always Indicative of Benign Prognosis. Epilepsia, 25(5):653, 1984.

McJilton JS, Ramsay RE, Vasquez D and Resillez M. Use of Bromide in Patients with Intractable Seizure Disorders. Epilepsia, 26(5):533, 1985.

Ramsay RE, Guterman A, Vasquez D and McJilton JS. Efficacy of Progabide in Uncontrolled Seizures: A Double-Blind Crossover Study. Epilepsia, 26(5):538, 1985.

Wilder BJ, Ramsay RE, Brown T and Sackellares JC. A Multicenter Double Blind Placebo Controlled Study on Zonisamide on Medically Refractory Patients With Complex Partial Seizures. Epilepsia, 26(5):547, 1985.

Honig L, Ramsay RE, Resillez M, Sazant A, Sheremata, WA, Wong P. Magnetic Resonance Imaging (MRI), Cognitive Impairment, and the P300 Event-Related Potential (ERP) in Patients with Multiple Sclerosis (MS). Neurology, 36(4):157, 1986.

Abou-Khalil BW, Berent S, Brown TR, Guterman A, Howard GS, Ramsay RE, Sackellares JC, Wagner J and Wilder BJ. Double-blind, Placebo-controlled Clinical Trial of Zonisamide in Complex Partial Seizures. Neurology, 36(4):85, 1986.

Pellock JM, Ramsay RE, Garnett WR, Sanchez R, Marcos J, Valakas A, McJilton J, Depot M, Williams, T and Cloutier G. Chronic Dose Tolerance of Lamotrigine in Epileptic Patients. Epilepsia, 27(5):647, 1986.

Lai A, Wargin WA, Garnett WR, Ramsay RE, Pellock JM, Vasquez D, Hubbell JP. Pharmacokinetics of Lamotrigine in Epileptic Patients Following Multiple Oral Dosing. Epilepsia, 27(5):647, 1986.

Sanchez RM, Marcos JL, Ramsay RE, Vasquez D, Guterman A, Riddle G, McJilton J, Wilder BJ, Sackellares, C and Brown T: Pharmacokinetics of Zonisamide: A New Anticonvulsant. Epilepsia, 27(5):647, 1986.

Honig LS, Ramsay RE and Sheremata WA: Topographically Mapped EEG and Event-Related Potentials (ERP) Correlate with Cerebral Involvement in Patients with Multiple Sclerosis (MS). EEG Clin Neurophys, 65:75P, 1986.

Fernandez-Gatti E, Sanchez RM, Ramsay RE and Norenberg MD. Sporadic Neuronal Ceroid Lipofuscinosis with Anterior Horn Cell Involvement, Axonal Peripheral Neuropathy, and Visual Loss. Neurology, 37(Suppl 1):356, 1987.

Ramsay RE, Sanchez RM, Guterman A, Krall R and Maldonado A. Placebo Effect: Fluctuation in Seizure Frequency During Placebo Treatment. Neurology, 37(Suppl 1):349, 1987.

Fariello R, Bruni J, Homan R, Jones M, Katz L, I. Leppik, Leroy R, Ramsay R N. Sussman and Krall R. A Double-Blind, Placebo-Controlled Trial of Progabide in Epilepsy. Neurology, 37(Suppl 1):350, 1987.

Maldonado A, McJilton J, Sanchez RM, Guterman A, Resillez M and Ramsay R. Prospective Long-term Outcome of Patients with Epilepsy. Neurology, 37(Suppl 1):101, 1987.

Ramsay RE, Pellock JM, Wilder BJ, Mattson RH, Dreifuss FE, Smith DB, Penry JK, Leroy RF, Acosta O and Bush MA. Conversion from Polypharmacy to Monotherapy with Depakote in Patients with Primary Generalized Tonic-Clonic Seizures. Epilepsia, 28:607, 1987.

Bender A, Ramsay RE, Roque M, McJilton JS and Sanchez RM. Clinical Features and Medical Background in Patients with Pseudoseizures. Epilepsia, 285:613, 1987.

Maldonado A, Rangel R, Ramsay RE, Wilder BJ, Sanchez RM, Guterman A, Spieth J and Gomez F. Prospective Long-Term Outcome of Patients with Epilepsy. Epilepsia, 28:624, 1987.

McJilton JS, Sanchez RM, Guterman A, Pryor F, Acosta O, Ramsay RE. Toxicity and Efficacy of Mephenytoin. Epilepsia, 28:589, 1987.

Mattson RH and the VA Epilepsy Cooperative Study Group. Study Design for a Multicenter Antiepileptic Drug Trial of Carbamazepine versus Valproate. Epilepsia, 28:605, 1987.

Ramsay RE and Resillez M. Post-Chiasmatic Visual Pathway Effects Demonstrated by Topographic Mapping of Pattern Reversal Evoked Potentials. EEG Clin Neurophysiol, 69:80P, May 1988.

Ramsay RE, Guterman A, and Resillez M. Event Related Potentials: Results of Topographic Mapping in Normal Controls and Patients Post Temporal Lobectomy. EEG Clin Neurophysiol, 69:80P, May 1988.

Guterman A, Ramsay RE, Resillez M, Maldonado A, Szapacznick J, Million C and Eisdorfer C. Multichannel Cognitive Evoked Responses in Neurologically Normal HIV-Positive Males, Neurology, 38(Suppl 1):98, 1988.

Bender A, Ramsay RE and McJilton J. Seizures in Patients with an Initial Non-Epileptiform Scalp EEG, Epilepsia, 29(5):664, 1988.

McJilton J, Mendia O, Vega M, Resillez M and Ramsay RE. Accuracy and Documentation of Patients AED Regimen, Epilepsia, 29(5):670, 1988.

Prevey ML, Delaney RC, Mattson RH, Cramer JA and the VA Epilepsy Cooperative Study Group. Cognitive Functioning in Seizure Patients Prior to Treatment with Antiepileptic Drugs. Epilepsia, 29:692, 1988.

Ramsay RE, Wilder BJ, Mattson RM, Dreifuss FE, Pellock JM, Smith DB, Ahmann PA, Spitz MC, Penry JK, Leroy RF, Murphy JV and Sunder TR. Conversion from Polypharmacy to Monotherapy with Depakote in Patients with Primary Generalized Tonic-Clonic Seizures, Epilepsia, 29(5):699, 1988.

Ramsay RE, Pellock JM, Wilder BJ, Mattson RH, Dreifuss FE, Smith DB,Penry JK, Leroy RF, Acosta O and Bush MA. Successful Valproate Monotherapy in Patients with Tonic-Clonic Seizures, Neurology, 38(Suppl 1):104, 1989.

Wilder BJ, Ramsay RE, Maldonado A, Murphy JV and Pierce MW. The Efficacy and Safety of Valproic Acid Compared to Phenytoin as Sole Therapy for Tonic-Clonic Seizures in Newly Diagnosed Patients, Neurology, 39(Suppl 1):328, 1989.

Ramsay RE, Wilder BJ, Pellock JM, Dreifuss F, Mattson RH, Smith DB, Penry JK, Sunder TR, Ahmann PA, Spitz MC, Murphy JV, Leroy RF, Morris DD, Hanson R and Pierce MW. Successful Conversion from Polypharmacy to Depakote Monotherapy in Patients with Primary Generalized Seizures, Epilepsia, 30(5):662, 1989.

Ramsay RE, Wilder BJ, Murphy JV, Holmes GL, Uthman B, Morris, Shu VS and Pierce MW. Efficacy of Valproate vs. Phenytoin in the Treatment of Patients with Newly Diagnosed Tonic Clonic Seizures. AES Boston, Dec. 1989.

Ramsay RE, Guterman A, Mcmanus D, McJilton J, Faleck H, Strollo A, Thakker K, Mangat S and Hakkarainer H. Comparative Pharmacokinetics of Tegretol Controlled Release System to Tegretol in Epileptic Patients, Epilepsia, 30(5):638, 1989.

Slater JD, Singer C and Ramsay RE. Parkinson's Disease and Epilepsy: An Epidemiological Survey. Epilepsia, 31(5):604, 1990.

Risner M, LAMICTAL Study Group, Burroughs Wellcome Co. A Multicenter, Double-Blind, Placebo (PBO) - Controlled, Add-On, Crossover Study of Lamotrigine(LAMICTAL, LTG) in Epileptic Outpatients with Partial Seizures. Epilepsia, 31(5):619, 1990.

Treiman DM, Meyers PD, Collins JF, Colling C and the VA Status Epilepticus Cooperative Study Group: RE Ramsay, et al. Design of a Large Prospective Double-Blind Trial to Compare Intravenous Treatments of Generalized Convulsive Status Epilepticus. Epilepsia, 31:629, 1990.

Treiman DM and the VA Status Epilepticus Cooperative Study Group: RE Ramsay, et al. Genetics of Symptomatic Partial Epilepsy. Epilepsia, 31:819, 1990.

Cramer JA, Scheyer RD, Hochholzer JS, Mattson RH and the VA Epilepsy Cooperative Study #264 Group. Carbamazepine Concentrations and Adverse Effects. Epilepsia 31:819, 1990.

Ramsay RE, Avery A, Gallo BV, Slater J and McManus D. Safety and Kinetics of Intramuscular Valproate. Epilepsia, 31(5):654, 1990.

Ramsay RE, Uthman BM, Leppik I, Pellock J, Wilder BJ, Garnett W and Grosz R. Cardiovascular Safety and Tolerance of Intravenous Sodium Valproate as Replacement Therapy for Oral Divalproex Na: A Double-Blind Placebo-Controlled Study. Epilepsia, 31(5):618, 1990.

Wilkie F, A Guterman, RO Morgan, RE Ramsay and C Eisdorfer. Cognition and Electrophysiologic Measures in Early HIV Infection. J Clin Exper Neuropsych, 12(1):48, 1990.

Cramer JA, Scheyer RD, Hochholzer JS, Mattson RH and the VA Epilepsy Cooperative Study #264 Group. Carbamazepine Assay Cross-Reactivity. Neurology 40(Suppl 1):138, 1990.

Uthman B, Wilder BJ, Gainesville, FL; Penry R, Winston-Salem, NC; Ramsay RE, Miami, FL; Tarver B, and Wernicke JF, Webster, TX. Treatment of Epilepsy by Modulation of l Activities. Neurology, 41(3)Suppl 1:195, 1991.

Ramsay RE, Wallace J, Shellenberger K, Wibberg M. Efficacy and Safety of Gabapentin (Neurotin) as Add-On Therapy in Patients with Uncontrolled Partial Seizures. Neurology, 41(3)Suppl 1:330, 1991.

Mattson RH, Cramer JA, Collins JF, and the VA Epilepsy Cooperative Study #264 Group. Comparison Between Carbamazepine and Valproate for Complex Partial and Secondarily Generalized Tonic-Clonic Seizures. Epilepsia, 32:18, 1991.

Uthman B, Slater J, Hammond E, Gallo BV, McJilton JS, Wilder BJ and Ramsay RE. Safety and Tolerability of Vagal Stimulation. Epilepsia, 32(Suppl 3):90, 1991.

Ramsay RE, Uthman B, Ben-Menachem E, Slater J, Erik Aug.inssen L,Landy H, Reid S, Hammond E, Andersen O, Gallo BV, McJilton JS and Wilder BJ. Efficacy of Vagal Nerve Stimulation in Partial Seizures: Double-Blind Comparison of Two Stimulus Paradigms. Epilepsia, 32(Suppl 3):90, 1991.

Aranguiz C, McJilton JS, Vega M and Ramsay RE. Safety and Effectiveness of Three Oral Doses of Topiramate in the Treatment of Patients with Refractory Partial Epilepsy. Epilepsia, 32(Suppl 3):11, 1991.

Ben-Menachem E, Hamberger A, Hedner T, Hammond EJ, Uthman RM, Slater JD, Ramsay RE, Wilder BJ. The Effects of Vagus Nerve Stimulation on Concentrations in the CSF of 5-Hydroxy Indoleacetic Acid, Homovanillic Acid, GABA, and Other Amino Acids in Patients with Partial Epilepsy. Epilepsia, 32(Suppl 3):90, 1991.

Treiman DM, Meyers PD, and the VA Status Epilepticus Cooperative Study Group: RE Ramsay et al. Utility of the EEG Pattern as a Predictor of Success in the Treatment of Generalized Convulsive Status Epilepticus. Epilepsia, 32(Suppl 3):93, 1991.

Treiman DM, Meyers PD, Walton NY, and the VA Status Epilepticus Cooperative Study Group: RE Ramsay, et al. Response of Overt Versus Subtle Generalized Convulsive Status Epilepticus to Intravenous Anticonvulsant Therapy. Epilepsia, 32(Suppl 3):93, 1991.

Mattson RH, Cramer JA, and the VA Epilepsy Cooperative Study Groups. Seizure Remission in Adults with Epilepsy. Neurology, 42(Suppl 3):243, 1992.

Cramer JA, Mattson RH and the VA Epilepsy Cooperative Study #264 Group. Laboratory Test Abnormalities During Long-Term Use of Carbamazepine and Valproate. Neurology, 42(Suppl 3):331, 1992.

Landy HJ, Slater J, Uthman B, Reid S, Casiano R, Wilder BJ and Ramsay RE. Vagus Nerve Stimulation for Complex Partial Seizures. Submitted for presentation at the American Association of Neurological Surgeons annual meeting, San Francisco, Apr. 1992. (In press).

Lundy DS, Casiano RR, Gallo J, Gallo BV, Ramsay RE and Landy HJ. Effects of Vagal Nerve Stimulation on Laryngeal Function. Submitted for presentation at the "Care of the Professional Voice" annual conference, Philadelphia, Summer 1992. Journal of Voice (In press).

Slater JD, Lundy DS, Casiano RR, Landy H, Gallo BV, LoPresti J and Ramsay RE. Vagus Nerve Stimulation Effects on Laryngeal Function. Epilepsia, 33(Suppl 3):101, 1992.

Slater JD, Wu FY and Ramsay RE. Neural Network Analysis of the P300 Cognitive Evoked Potential in Epilepsy, Multiple Sclerosis and Parkinson's Disease. Epilepsia, 33(Suppl 3):60, 1992.

Aranguiz C, Nemire R, Slater JD, Jallad NS, LoPresti J and Ramsay RE. Idiokinetic Propanolol Valproate Drug Interaction. Epilepsia, 33(Suppl 3):110, 1992.

Ramsay RE, Ben-Menachem E, Upton A, Ristanovic R and NCP Study Group. One-Year Follow-up of 29 Patients With Refractory Epilepsy Treated in a Controlled Study of Vagal Stimulation. Epilepsia, 33(Suppl 3):102, 1992.

Landy HJ, Ramsay RE, Slater J, Casiano RR and Morgan R. Vagus Nerve Stimulation for Complex Partial Seizures: Surgical Technique, Safety, and Efficacy. Accepted for presentation at the Congress of Neurological Surgeons Annual Meeting, Washington D.C., Oct. 31-Nov. 5, 1992.

Uthman BM, Ramsay RE, Wilder BJ and Hammond EJ. Two-Year Follow-up of Pilot Study Patients Receiving Vagal Stimulation for Partial Epilepsy. Epilepsia, 33(Suppl 3):102, 1992.

Messenheimer JA, Ramsay RE, Leroy RF, Zielinski JJ, Willmore LJ, Pellock JM, Mattson R, Rudd GD and Keaney PA. Multicenter, Long-Term Study of Lamotrigine (Lamictal) in Outpatients with Partial Seizures. Epilepsia, 33(Suppl 3):82, 1992.

Treiman DM, Gunawan S, Walton NY, Meyers PD and the DVA Status Epilepticus Cooperative Study Group: RE Ramsay et al. Serum Concentrations of Antiepileptic Drugs Following Intravenous Administration for the Treatment of Status Epilepticus. Epilepsia, 33(Suppl 3):3, 1992.

Treiman DM, Meyers PD, Walton NY, and the DVA Status Epilepticus Cooperative Study Group: RE Ramsay, et al. Duration of Generalized Convulsive Status Epilepticus (GCSE): Relationship to Clinical Symptomatology and Response to Treatment. Epilepsia, 33(Suppl 3):66, 1992.

Wilder BJ, Slater J, Malon J, Campbell K, Gilmore R, Uthman BM, Perchalski RJ and Ramsay RE. Parenteral Loading and Maintenance of Phenytoin with Fosphenytoin, a Phenytoin Prodrug. Epilepsia, 34(Suppl 2):27, 1993.

Ramsay RE, Slater JD, Cox M. Neurocardiogenic Syncope Successfully Treated with Valproate. Epilepsia, 34(Suppl 2):86, 1993.

Slater JD, Brown MC, Ramsay RE, Jacobs W. Intravenous Normal Saline Placebo Induction in Patients with Epilepsy and Pseudoseizures. Epilepsia, 34(Suppl 2):114-115, 1993.

Slater JD, Wu Fy and Ramsay RE. Neural Network Analysis of the P300 Cognitive Evoked Response in Temporal Lobe Epilepsy. Epilepsia, 34(Suppl 2):130, 1993.

Uthman BM, Ramsay RE, Naritoku D, Manon-Espaillat R and Sonnen AEH. One-Year Efficacy Results of Therapeutic Vagus Nerve Stimulation (VNS) in 61 Epilepsy Patients. Epilepsia, 34(Suppl 2):192, 1993.

Uthman B, Ben-Menachem E, Ramsay RE, Naritoku D and Hufnagel A. 18 Month Follow-up of 32 Epilepsy Patients Receiving Vagus Nerve Stimulation (VNS). Neurology, 43(Suppl 2):A161, 1993.

Wilder BJ, Ramsay RE, Marriott J, Loewen G and Smith H. Safety and Tolerance of Intramuscular Administration of Fosphenytoin, A Phenytoin Prodrug, for 5 Days in Patients with Epilepsy. Neurology, 43(Suppl 2):A308, 1993.

Slater J, Ramsay E, Barolat G, Rosenfeld W and Willis J. One Year Results of Vagus Nerve Stimulation (VNS) in 82 Refractory Epilepsy Patients. Accepted for presentation at the XVth World Congress of Neurology, Vancouver, Canada, Sept. 1993.

Wilder BJ, Ramsay E and Naritoku D. Follow-Up of 53 Refractory Epilepsy Patients Receiving Vagus Nerve Stimulation for 18 Months. Epilepsia, 34(Suppl 6):29, 1993.

Ramsay RE, Slater JD, Aranguiz C, Vega M, Ortiz WR, Ayala R, Lalama H and Rask C. Open Treatment with Tiagabine and Conversion to Monotherapy of Patients with Uncontrolled Partial and Generalized Seizures. Epilepsia, 34(Suppl 6):103, 1993.

Ramsay RE, Slater JD, Brown MC, Vega M, Aranguiz C and Rask C. Double-Blind Three Dose Parallel Placebo Controlled Efficacy of Tiagabine in Partial Seizures. Epilepsia, 34(Suppl 6):103 104, 1993.

Nemire RE, Ortiz WR, Ayala R, Slater JD and Ramsay RE. Effectiveness of Clobazam in Refractory Seizures. Epilepsia, 34(Suppl 6):41, 1993.

Brown MC, Slater JD, Ramsay RE and Landy HJ. Does Withdrawal of Anticonvulsant Medication Obscure Neuropsychological Data in Focal Epilepsy. Epilepsia, 34(Suppl 6):86, 1993.

Slater JD, Wu FY, Meador KJ, Ramsay RE. Neural Network Analysis of the P300 Event-related Potential in Healthy Subjects in the Drug versus Nondrug State. Epilepsia, 34(Suppl 6):136, 1993.

Jacobs W, Ramsay RE, Slater JD, Brown MC, Nemire RE, Ortiz WR, Ayala R, LoPresti J. Contribution of Family Patterns of Unsuccessful Medical Treatment of Epilepsy. Epilepsia, 34(Suppl 6):10, 1993.

Treiman DM, Meyers PD, Walton NY, and the DVA Status Epilepticus Cooperative Study Group: RE Ramsay, et al. Factors that Predict Prognosis in Generalized Convulsive Status Epilepticus. Epilepsia, 34(Suppl 6)30-31, 1993.

Yagnik P, Walton NY, Treiman DM and the DVA Status Epilepticus Cooperative Study Group: RE Ramsay et al. Electroencephalographic (EEG) Changes During Human Generalized Convulsive Status Epilepticus. Epilepsia, 34(Suppl 6):52, 1993.

Philbrook B, Toledo C, Willer JA, Ramsay RE and Slater JD. An Open Trial of Gabapentin Monotherapy in Patients with Uncontrolled Partial and Secondarily Generalized Seizures. Epilepsia, 35(Suppl 8):97, 1994.

Ramsay RE, Rowan AJ, Slater JD, Collins J, Nemire R, Ortiz WR and the VA Cooperative Study Group. Effect of Age on Epilepsy and Its Treatment: Results from the VA Cooperative Study. Platform presentation at AES Scientific Program, New Orleans, Dec. 1994. Epilepsia, 35(Suppl 8):91, 1994.

Slater JD, Morgan R, Nemire R, Ortiz WR, Rowan AJ, and Ramsay RE. Medical Economics of Epilepsy: Analysis of South Florida Medicare Database. Epilepsia, 35(Suppl 8):48, 1994.

Jacobs W, Fowers B, Siskind J, Ramsay RE, Landy HJ and Slater JD. Epilepsy: Family Evaluation and Treatment. Epilepsia, 35(Suppl 8):56, 1994.

Uthman BM, Wilder BJ, Ramsay RE, Naritoku D and Ben-Menachem E. Eighteen Month Follow-up of 76 Refractory Epilepsy Patients Receiving Vagus Nerve Stimulation. Epilepsia, 35(Suppl 8):90, 1994.

Devinsky O, Leppik I, Willmore LJ, Pellock JM, Dean C, Gates J, Ramsay RE and the IV Valproate Study Team. Safety of Intravenous Valproate. Epilepsia, 35(Suppl 8):144, 1994.

Rowan AJ, Dane S, Price H, Scarpa J, Sanna PM, Ortiz W, Nemire R and Ramsay RE. A Pilot Epidemiologic Study of Long-Stay Elderly Patients with Seizures. Epilepsia, 35(Suppl 8):111, 1994.

Jacobs W, Ramsay RE, Landy H, Slater D and Fowers B. Development of a Medical Family Therapy Program in a Comprehensive Epilepsy Center. Accepted for presentation at the American Orthopsychiatric Association annual meeting, Chicago, Apr. 1995.

Ramsay RE, Barkley GL, Garnett WR, Pellock JM, Leppik IE, Wilder BJ and Uthman B. Safety and Tolerance of Intramuscular Fosphenytoin (Cerebyx) in Patients Requiring a Loading Dose of Phenytoin. Accepted for poster presentation at AAN meeting, Seattle, Washington, May 1995.

Ramsay RE on behalf of the Intravenous Valproate Safety Study Investigators. Evaluation of the Safety of Intravenous Valproate. Epilepsia, 36(Suppl 3):S67, 1995.

Devinsky O and Ramsay RE. The Safety of Intravenous Valproate. Epilepsia, 36(Suppl 3):S67, 1995.

William J Jr., Fowers B, Callerame KJ, Brown MC, Philbrook B, Martinez OA, McJilton JS and Ramsay E. Factors Influencing Outcome in Patient with Non-epileptic seizure. Epilepsia, 36(Suppl 4): 162, 1995.

Philbrook B, Martinez OA, Callerame KJ, Toledo C, Gonzalez JG and Ramsay RE. Efficacy of Lamotrigine in Patients with Primary Generalized Epilepsy: A Retrospective Study. Epilepsia, 36(Suppl 4): 66, 1995.

Ramsay RE, Philbrook B, Martinez OA, Callerame KJ, Gallo BV and Acosta A. A Double Blinded, Randomized Safety Comparison of Rapidly Infused Intravenous Loading Doses of Fosphenytoin vs. Phenytoin. Epilepsia, 36(Suppl 4): 52, 1995.

Callerame KJ, Toledo C, Martinez OA, Philbrook B, Ramsay E, Gonzalez JG. Gabapentin Serum Levels in Patients on Doses Greater Than 1800 mg/day. Epilepsia, 36(Suppl 4): 70, 1995.

Martinez OA, Vega M, Philbrook B, Callerame KJ, Ramsay RE. Acute Chronic, and Dose Related Side Effects with Gabapentin. Epilepsia, 36(Suppl 4): 71, 1995.

Fraught E, Wilder BJ, Ramsay RE, Reife RA, Kramer LD, Pledger GW, Karim RM and the Topiramate YD Study Group. Topiramate Dose-Ranging Trial in Refractory Partial Epilepsy. Epilepsia, 36(Suppl 4): 33, 1995.

Rowan AJ, and Ramsay RE. Epilepsy in the Elderly. Epilepsia, 36(Suppl 3): S131, 1995.

Ramsay RE, for the Intravenous Valproate Safety Study Investigators. Evaluation of the Safety of Intravenous Valproate. Epilepsia, 36(Suppl 3): S67, 1995.

Walton NY, Treiman DM, Meyers PD and the DVA status epilepticus cooperative study group, Ramsay RE. Outcome after generalized convulsive status epilepticus following cardiopulmonary arrest. Neurologogy, 46():A325, Feb 1996.

Cloyd JC, and Ramsay RE. New and Old Antiepileptic Drugs in the Elderly. Submitted to the Third EILAT Conference on New Antiepileptic Drugs 1996 meeting.

Morgan R, Ramsay E, Virnig B, and DeVito C. Epilepsy and Excess Risk for Mortality Following Inpatient Admissions. Epilepsia, 37(Suppl 5): 82, 1996

Ramsay RE, Greiner MJ, DeToledo J, Garofalo EA, and the US GBP Study Group 82/83. Conversion to Gabapentin (GBP; Neurontin7) Monotherapy: Carbamazepine (CBZ), Valproate (VPA) and Phenytoin (PHT) Antiepileptic Withdrawal Effects. Epilepsia, 37(Suppl 5): 160, 1996.

Garofalo EA, Hartman T, Hayes A, Koto EM, LaMoreaux LK, and the US GBP Study Group 82/83. Weight Changes During a Gabpentin (Neurontin7) 26 Week Monotherapy Trial (945-82). Epilepsia, 37(Suppl 5): 160, 1996.

McJilton J, DeToledo J, DeCerce J, Huda S, Abubakr A, and Ramsay RE. Cotherapy of Lamotrigine/Zonisamide Results in Significant Elevation of Zonisamide Levels. Epilepsia, 37(Suppl 5): 173, 1996.

DeToledo J, Toledo C, Ramsay RE, Rowan AJ, Uthman B, DeCerce J, Huda S, and Abuhuzeifa A. Conversion to Lamotrigine Monotherapy: Efficacy and Tolerability of Previous Inducing/Non Inducing AEDs on the Initiation Rates in Patients with Refractory Primary and Secondarily Generalized Seizures. Epilepsia, 37(Suppl 5): 163, 1996.

Mitchell WG, Shellenberger K, Groves L, Cereghino J, MurphyJ, Rosenfeld W, Farwell JR, and the Diastat Study Group. Rectal Diazepam Gel (Diastat7)for Acute Repetitive Seizures: Results of a Double-Blind, Placebo-Controlled Study in Children and Adults with Epilepsy. Epilepsia, 37(Suppl 5): 1996.

Groves L, Shellenberger K, Franklin J, and the Diastat Study Group. Safety and Tolerability of a Single Dose Administration of Diastat7 (Diazepam Rectal Gel) to Patients with Epilepsy on Antiepileptic Drugs (AEDs). Epilepsia, 37(Suppl 5): 1996.

Treiman DM, Meyers PD, Walton NY, Collins JF and the DVA Status Epilepticus cooperative Study Group, Ramsay, RE. Treatment of Generalized convulsive status epilepticus: a multicenter comparison of four drug regimens. Neurology, 46(2): A219; Feb 1996.

Ramsay RE, Philbrook B, Fischer JH, Sloan EP, Allen FH, Runge JW, Smith MF, and Kugler AR. Safety and pharmacokinetics of fosphenytoin (Cerebyx) compared with dilantin following rapid intravenous administration. Neurology, 46(2): A245; Feb 1996.

DeToledo J, Ramsay RE & Ajmone Marsan C. the lunatic and his seizure (Historical Neurology). Neurology, 47: 292-293, 1996.

DeCerce J, DeToledo J, Lowe, Ramsay RE. Outcome of video/EEG telemetry in a cohort of tertiary referral patients admitted for diagnosis: role of placebo induction. Epilepsia, 38(Suppl 8): 60; 1997.

Ramsay RE, Toledo C, DeToledo J, and Lowe M. Conversion to lamotrigine monotherapy in patients with uncontrolled primary (PGE) and secondarily generalized epilepsy with follow-up to 6 months. Epilepsia, 38(Suppl 8): 207; 1997.

Lowe M, DeToledo J, DeCerce J, Toledo C, Jacobs W and Ramsay RE. Placebo induced nonepileptic events (NES) identical to the simple partial seizures in patients with intractable epilepsy. Epilepsia, 38(Suppl 8): 62; 1997.

Toledo C, Puig A, DeToledo J, Lowe M, DeCerce J and Ramsay RE. Non epileptic seizures (NES) during pregnancy. Epilepsia, 38(Suppl 8): 62; 1997.

Rowan A James, Ramsay R. Eugene, Collins Joseph F., Smith Bonnie W, & DVA CS 428 studey group. Treatment of seizures in the elderly population: a new DVA copperative study. Epilepsia, 38(Suppl 8): 89; 1997.

Wilder BJ, French JA, Ramsay RE, Bergen C and Padgett CS. Zonisamide introduction and tolerance. Epilepsia, 38(Suppl 8): 108; 1997.

The Diastat Group, Rectal diazepam gel (diastat) in the treatment of children with acute repetitive seizures. 27th Annual meeting of Child Neurology Society, Oct 21-24, 1998, Montreal Canada.

Gallo BV, Gidal BE, McJilton JS, and Ramsay RE. Safety & Pharmacokinetic Profile of High Dose IV Bolus Administration of Valproic Acid (Depacon7). Epilepsia, 39(Suppl 6): 49-50, 1998.

Ramsay RE, Gidal B, Toledo C, Lowe MR, DeToledo J, and Pryor FM. Pharmacokinetics of Load Dose of IM Fosphenytoin and Double-Blind Comparison of Tolerance vs. IM Saline. Epilepsia, 39(Suppl 6):46-47, 1998.

Jacobs W, Lowe MR, Ramsay RE, and DeToledo J. NES: Factors to Target for Diagnosis and Treatment. Epilepsia, 39(Suppl 6): 226, 1998.

Lowe MR, DeToledo JC, Vilavizza N, and Ramsay RE. Efficacy, Safety and Tolerability of Fast IV Loading of Valproate in patients with Seizures and Status Epilepticus. Epilepsia, 39(Suppl 6): 235, 1998.

DeToledo, JC, Mitrani R, Lowe MR, Puig A and Ramsay RE. Non-Epileptic Seizures and Neurocardiogenic Syncope. Epilepsia, 39(Suppl 6): 242-243., 1998.

Jacobs, William Jr., Lowe, MR, Ramsay R., and DeToledo, JC. A Prospective study for Diagnosis and Treatment of N.E.S., using a structured interview and treatment format (SRJSITF) Epilepsia, 40 (Suppl 7): 64, 1999.

Pryor, Flavia M., Ramsay R.E., Rowan, A. James, and Collins, Joseph F, VA Coop Study Group #428. Treatment of Seizures in the Elderly: Retention and Diagnosis Epilepsia, 40 (Suppl 7): 106, 1999.

Gidal, Barry E., Sheth, Raj D., Bainbridge, Jacquelyn, Ramsay, RE., Welty, Timothy E., Weatherford, Karen J., Gilliam, frank, Gallo, Bruno V., Alldredge, Brain K., Montouris, Georgia D., Belden, Daryn S., and Lenners, Annette Alternative Medicine (AM) use in Epilepsy:Results of a National, Multicenter Survey Epilepsia, 40 (Suppl 7): 107-108, 1999.

Beydoum, Ahmad, Arbor, Ann, Uthman, basin M., Ramsay, RE., Smith, Tzena M., Greiner, Martha J., Knapp, Lloyd E., Bockbrader, Howard N. and Garofalo, Elizabeth Pregabalin add-on Trail: A Double-Blind, Multi-center Study in Patients with Partial Epilepsy Epilepsia, 40 (Suppl 7): 108, 1999.

Ramsay, RE., Velso, Felix, Bomhof, Maritn AM, Ziekenhuis, Innatius, Pleger, Gordon and Wu, Shu Chen Patient Factors Affecting response to early AED Monotherapy in Partial-onset seizures: Observations from a randomized controlled trail with Topiramate (TPM) Epilepsia, 40 (Suppl 7): 111, 1999.

Ramsay, RE., Velso, Felix, Bomhof, Maritn AM, Ziekenhuis, Innatius, Pleger, Gordon and Wu, Shu Chen Patient Factors Affecting response to early AED Monotherapy in Partial-onset seizures: Observations from a randomized controlled trail with Topiramate (TPM) Epilepsia, 40 (Suppl 7): 111, 1999.

Pryor Flavia M, R Eugene Ramsay, A James Rowan, Joseph F Collins, & VA Coop Study Group #428. Diagnostic, Demographic, and Retention Issues in Managing Seizures in Older Patients. Neurology 54:(Suppl 3):A84-A85, April 2000

Vega M, Jeanee McJilton, .R Eugene Ramsay, Wayne Johnson, John DeToledo, Merredith R Lowe. Efficacy and safety of long term treatment of refractory epilepsy with pregabalin. Epilepsia 41(Suppl 7): 88-89, 2000

Johnson Juanita, Flavia M , .R Eugene Ramsay, A James Rowan, John DeToledo, VA Coop Study Group #428. Clinical trials: recruitment challenges in the elderly. Epilepsia 41(Suppl 7): 109, 2000

Pryor Flavia M, .R Eugene Ramsay, Charles E Pippenger, Juanita Johnson. Free radical balance in post-traumatic epilepsy. Epilepsia 41(Suppl 7): 171, 200

Ramsay R Eugene, A James Rowan, Joseph Collins, VA Coop Study Group #428. Seizures in the older patient: Demographics, diagnosis, and treatment. Epilepsia 41(Suppl 7): 182-173, 2000

Decerce John, Jeanee McJilton, Mangala A Nadkarni, .R Eugene Ramsay, Wayne Johnson, John DeToledo, Merredith R Lowe. Lamotrigine-vlaproate interaction: relationship to dose of valproage. Epilepsia 41(Suppl 7): 220-221, 2000

McJilton Jeanee, .R Eugene Ramsay, David Vasquez, B J Wilder, Chris Sachellares, Thomas Browne. Pharmacokinetics of zonisamide: results from a randomized double-blind multicenter placebo controlled study.. Epilepsia 41(Suppl 7): 224, 2000

Cantrell Deborah,.R Eugene Ramsay, Stephen D Collins, Julia K Walch, Yihua Gu, roger Deaton, Dean K Naritoku, John Gates, Ruben I Kuxniecky, George L Morris, James C Cloyd, Henry Raroque. Rapid infusions of depacon are safe and well tolerated. Epilepsia 41(Suppl 7): 253, 2000

Beydoun Ahmad A, Basim M Uthman,.R Eugene Ramsay, Tzena M Smith, Michaele K Dumetz, Martha J Greiner, Susan Henkin, Lloyd E Knapp, Elizabeth A Garofalo, the Pregabilin 9/10 study group. Pregabalin add-on trial: double-blind, multi-center study in patients with partial epilepsy. Epilepsia 41(Suppl 7): 253-254, 2000

Spitz Mark, Jacquelyn Bainbridge, R Eugene Ramsay, Basim Uthman, Flavia M. Pryor, Brenda Smith, VA Coop Study Group #428. Observations on the delay in the diagnosis of seizure in the elderly. Epilepsia 41(Suppl 7): 109, 2000



Under Review:
Sloan EP, Luer MS, Fischer JH, Ramsay RE, Runge JW, Philbrook B, and Allen FH. Cardiac Effects with High-Dose, High-Rate IV Fosphenytoin Seizure Therapy. Submitted to SAEM May 1997 meeting.


Other works accepted for publication:

Montorous GD & Ramsay, RE., Teaching Monograph - New developments in the treatment of epilepsy CNS Spectrums, 5(4): April 2000.


Grants received

Pharmacokinetics and Mechanism of Anticonvulsant Action
Veterans Administration Medical Center
Grant Years: June 1982 - Dec. 1986
Total Grant: $314,100

Efficacy and Toxicity of A Standard Antiepileptic Drug vs. Valproic Acid for Partial Seizures
Veterans Administration Medical Center
Grant Years: Jan. 1985 - May 1990
Total Grant: $110,144

Twenty-Eight Day Dose Tolerance Study of Lamotrigine in Epileptic Patients
Burroughs Wellcome Co.
Grant Years: Aug. 1985 - June 1986
Total Grant: $65,000

MK-801 in the Treatment of Partial Seizures
Merke, Sharpe & Dohme
Grant Years: Sept. 1985 - Aug. 1987
Total Grant: $65,000

Lamotrigine in Patients with Medically Refractory Complex Partial Seizures
Burroughs Wellcome Co.
Grant Years: Nov. 1986 - May 1988
Total Grant: $74,958

Conversion of Patients with Primary Generalized Seizures from Polypharmacy to Valproic Acid Monotherapy
Abbott Laboratories
Grant Years: Sept. 1986 - Sept. 1988
Total Grant: $68,820

A Multicenter, Double-blind, Placebo-Controlled Add-On Crossover Study of Lamotrigine in Epileptic Out-Patients with Partial Seizures
Burroughs Wellcome Co.
Grant Years: Oct. 1986 - Sept. 1988
Total Grant: $65,900

Efficacy of Gabapentin in Patients with Medically Resistant Partial Complex Seizures
Warner-Lambert
Grant Years: Apr. 1987 - May 1989
Total Grant: $99,700

A Multicenter, Open Continuation Study of Lamotrigine in Epileptic Outpatients with Partial Seizures
Burroughs Wellcome Co.
Grant Years: Sept. 1987 - Sept. 1989
Total Grant: $43,188

Quantified EEG Changes in HIV Infections
NIMH
Grant Years: Oct. 1987 - Sept. 1991
Total Grant: $200,000

Comparative Pharmacokinetics in Epileptic Patients Protocol 33
Ciba-Geigy
Grant Years: Nov. 1988 - Nov. 1989
Total Grant: $82,350

Long-Term Treatment with Topiramate YK-P and YK-T
Pharmaceutical Research Institute
Grant Years: Apr. 1989 - Mar. 1992
Total Grant: $25,000

Efficacy of Topiramate in the Treatment of Partial Seizures
McNeil Pharmaceutical Co.
Grant Years: May 1989 - Apr. 1992
Total Grant: $115,000

Efficacy of Felbamate in the Treatment of Partial Seizures
Carter-Wallace Co.
Grant Years: May 1989 - Apr. 1991
Total Grant: $25,920

Effect of Vagal Nerve Stimulation for the Control of Seizures in Humans
Cyberonics, Inc.
Grant Years: Jan. 1989 - Dec. 1992
Total Grant: $140,000

Safety and Effectiveness of the Neurcybernetic Prosthesis in the Treatment of Epilepsy
Cyberonics, Inc.
Grant Years: Apr. 1989 - Mar. 1992
Total Grant: $145,000

Pharmacokinetics of Sustained Release OROS-Tegretol
Ciba-Geigy
Grant Years: Aug. 1989 - Feb. 1990
Total Grant: $90,000

The Cardiovascular Safety and Tolerance of Intravenous Sodium Valproate as Replacement Therapy for Oral Depakote
Abbott Laboratories
Grant Years: Dec. 1989 - Sept. 1990
Total Grant: $109,050

Safety and Pharmacokinetics of Intravenous Valproic Acid
Abbott Laboratories
Grant Years: Feb. 1990 - Dec. 1991
Total Grant: $160,000

Open-Label Follow-On Long-Term Felbamate Therapy in Adult Subjects with Epilepsy
Carter-Wallace Co.
Grant Years: May 1990 - Apr. 1992
Total Grant: $30,678

A Multicenter, Open Label, Long-Term Evaluation of the Safety of Felbamate in Subjects with Epilepsy
Carter-Wallace Co.
Grant Years: May 1990 - Apr. 1992
Total Grant: $30,678

An Open Study of Lamictal in Epileptic Outpatients Protocol 17
Burroughs Wellcome Co.
Grant Years: May 1990 - Apr. 1994
Total Grant: $3,600

Neurocybernetic Prosthesis (NCP) for the Treatment of Epilepsy - Protocol EO3
Cyberonics, Inc.
Grant Years: June 1990 - May 1992
Total Grant: $181,250

Safety and Efficacy of Depakote Monotherapy in the Treatment of Complex Partial Seizures: A Plasma Concentration. Response Study
Abbott Laboratories
Grant Years: July 1990 - Dec. 1991
Total Grant: $46,813

Treatment of Generalized Convulsive Status Epilepticus
VA Cooperative Study #265
Veterans Administration Medical Center
Grant Years: Aug. 1990 - Aug. 1994
Total Grant: $105,000

Double-Blind, Randomized, Placebo-Controlled, Parallel Group Study of Vigabatrin in Patients with Uncontrolled Complex Partial Seizures
Marion Merrell Dow, Inc.
Grant Years: Aug. 1990 - Aug. 1992
Total Grant: $85,469

An Open, Long-Term Maintenance Study of Vigabatrin in Patients with Uncontrolled Complex Partial Seizures
Marion Merrell Dow, Inc.
Grant Years: Apr. 1991 - Mar. 1993
Total Grant: $71,562

A Five-Day, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Clinical Study of Tolerance and Safety of Multiple Doses of IM-administered CI-02
Warner-Lambert
Grant Years: May 1991 - May 1992
Total Grant: $58,875

The Safety of Intravenous Valproate
Abbott Laboratories
Grant Years: June 1991 - Dec. 1992
Total Grant: $19,688

Open Label Multicenter Study of the Safety & Tolerance of IM-Administered Multiple Dose Fosphenytoin in Hospitalized Neurosurgery Patients Protocol 14
Warner-Lambert
Grant Years: Jan. 1992 - Dec. 1992
Total Grant: $50,250

Safety and Efficacy of Three Dose Levels of Tiagabine HCl vs. Placebo as Adjunctive Treatment for Complex Partial Seizures M91-603
Abbott Laboratories
Grant Years: Jan. 1992 - Sept. 1993
Total Grant: $72,875

An Open-Label, Long-Term Safety Study of Vigabatrin Administered Concomitantly with Antiepilepsy Drugs or as Monotherapy
Marion Merrell Dow, Inc.
Grant Years: Apr. 1992 - Apr. 1994
Total Grant: $88,106

An Open-Label Extension Study of Tiagabine HC1 in the Treatment of Patients with Complex Partial Seizures Protocol M91-604
Abbott Laboratories
Grant Years: Sept. 1992 - Dec. 1997
Total Grant: $105,462
Conversion from Marketed Antiepileptic Drug Therapy to Gabapentin (CI-945) Monotherapy in Patients with Complex Partial or Secondarily Generalized Seizures: A Double-Blind, Dose Controlled, Multicenter Study Protocol 945-082
Parke-Davis Pharmaceuticals
Grant Years: Oct. 1992 - Jan. 1995
Total Grant: $78,000

An Open-Label Study of the Safety of Long-Term Tiagabine HC1 Administration in Patients with Epilepsy - Protocol M92-813.
Abbott Laboratories
Grant Years: Nov. 1992 - Dec. 1997
Total Grant: $48,125

A Long-Term, Open-Label, Extension Study of TOPIMAX Topiramate Protocol YLT
Pharmaceutical Research Institute
Grant Years: Nov. 1992 - Oct. 1993
Total Grant: $14,500

A Safety & Efficacy study of Extended Open-Label Gabapentin (CI-945) Monotherapy Following a Double-Blind Study in Patients with Complex Partial or Secondarily Generalized Seizures Protocol 945-083
Parke- Davis Pharmaceuticals
Grant Years: Jan. 1993 - Aug. 1996
Total Grant: $78,000

Baseline Controlled Safety and Efficacy Evaluation of Zonisamide in the Treatment of Seizures in Medically Refractory Patients - Protocol 810-920
Dainippon/IBRD
Grant Years: May 1993 - Dec. 1995
Total Grant: $68,400

Long-Term Safety and Efficacy Evaluation of Zonisamide in the Treatment of Seizures in Medically Refractory Patients and Efficacy Evaluation fo Zonisamide Monotherapy - Protocol 810-921
Dainippon/IBRD/Athena Neuroscience
Grant Years: May 1993 - ongoing
Total Grant: $118,210

Gabapentin In-Patients Monotherapy Trail: A Double-Blind, Dose Controlled, Multicenter Study in Patients with Refractory partial Epilepsy Protocol 945-088
Parke-Davis Pharmaceuticals
Grant Years: Mar. 1994 - Mar. 1996
Total Grant: $95,000

Gabapentin Open Label, Follow-On Trial in Patients with Refractory partial
Epilepsy Protocol 945-089.
Parke-Davis Pharmaceuticals
Grant Years: Mar. 1994 - Mar. 1996
Total Grant: $78,000

Long-Term Safety and Efficacy Evaluation for Zonisamide in the Treatment of Seizures in Medically Refractory Patients and Efficacy of ZNS Monotherapy - Protocol 810-922
Dainippon/IBRD
Grant Years: Apr. 1994 - Oct. 1996
Total Grant: $15,970

A Multicenter Double-Blind, Placebo-Controlled, Parallel-Design Evaluation of Lamictal for Add-On Treatment of Partial Seizures in Pediatric Patients #40
Burroughs Wellcome Co.
Grant Years: Apr. 1994 - Mar. 1996
Total Grant: $95,750

A Multicenter, Double-Blind, Active-Control Evaluation of the Efficacy and Safety of Lamotrigine Monotherapy in Patients with Partial Seizures Protocol 30
Pharmaceutical Research Institute
Grant Years: May 1994 - Aug. 1995
Total Grant: $62,688

Clinical Experience & Use of Sabril in Patients with Partial Seizures Protocol 098
Marion Merrell Dow, Inc.
Grant Years: July 1994 - Mar. 1998
Total Grant: $28,000

Safety and Efficacy of a Single, Rectal Administration of Diazepam for Acute Repetitive Seizures Protocol AN094-003
Athena Neurosciences
Grant Years: July 1994 - July 1995
Total Grant: $41,624
An Open-Label, Follow-On Study of the Safety and Efficacy of Intermittent Rectal Administration of Diazepam for Acute Repetitive Seizure Protocol AN094-004
Athena Neurosciences
Grant Years: July 1994 - July 1995
Total Grant: $5,368

Long-Term, Open-Label Study of Topiramate.
Pharmaceutical Research Institute
Grant Years: Sept. 1994 - June 1997
Total Grant: $58,425

An Open-Label Study of the Safety of Rectal Administration of Diazepam (Diastat7) in Patients with Epilepsy Protocol AN094-305
Athena Neurosciences
Grant Years: Jan. 1995 - Feb. 1996
Total Grant: $45,000

Conversion to Lamotrigine Monotherapy in Patients with Epilepsy
Burroughs Wellcome Co.
Grant Years: Jan. 1995 - Dec. 1995
Total Grant: $55,034

Safety and Efficacy of Tiagabine HCl as Adjunctive Treatment Protocol M92-825
Abbott Laboratories
Grant Years: Jan. 1995 - May 1997
Total Grant: $68,799

A Double-Blind, Randomized, Parallel-Group, Single-Dose, Multicenter, Safety, Tolerance, and Pharmacokinetic Study of Intravenous Fosphenytoin Versus Intravenous Dilantin in Patients Requiring A Loading Dose of Phenytoin - Protocol 026
Warner-Lambert/Parke-Davis
Grant Years: Mar. 1995 - July 1995
Total Grant: $29,750

A Multicenter Continuation of the Lamictal (Lamotrigine) Monotherapy Studies
Burroughs Wellcome Co./PRA (CRO)
Grant Years: Mar. 1995 - Feb. 1996
Total Grant: $5,136

Randomized, Double-Blind, Parallel-Design, Multicenter Trial to Evaluate Two Titration Rates of Oral Topamax in Subjects with Epilepsy Protocol TPS-TR
Ortho McNeil Pharmaceutical/Pharmaco LSR (CRO)
Grant Years: June 1995 - June 1997
Total Grant: $54,296

Topiramate (RWJ17021-000) Monotherapy Clinical Trial in Subjects with Recently Dianosed Partial-Onset Seizures Protocol TOPMAT-EPMN-104
R. W. Johnson Pharmaceutical Research Institute
Grant Years: Nov. 1995 - Ongoing
Total Grant: $20,548

Safety & Efficacy of Tiagabine HCl in the Treatment of Pediatric Patients with Partial Seizures Protocol M96-421
Abbott Laboratories
Grant Years: July 1996 - June 1998
Total Grant: $20,000

An Open-Label Extension Study of Tiagabine HCl in the Treatment of Pediatric Patients with Partial Seizures Protocol M96-460
Abbott Laboratories
Grant Years: Oct. 1996 - Ongoing
Total Grant: $20,000

An Open- Label Study of LAMICTAL in Patients Who Previously Participated in a LAMICTAL Pediatric Trial Protocol 105-41

Glaxo Wellcome Company Inc.
Grant Years: Oct. 1996 - Ongoing
Total Grant: $2,000

A Multi-Centre, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of SB204269 as Add-On Therapy in Patients with Refractory Simple or Complex Partial Seizures (with or without secondary generalization) Protocol 204269/008
SmithKline Beecham Pharmaeuticals
Grant Years: Oct. 1996 - Aug. 1998
Total Grant: $60,000

An Open-Label, Safety, Tolerance, & Pharmacokinetic Study of Intravenous & Intramuscular Fosphenytoin (Cerebyx7) in children Less Than 5 Years of Age Protocol 982-28
Parke-Davis Pharmaceutical
Grant Years: Nov. 1996 - Feb. 1998
Total Grant: $5,000

A Double-Blind, Double-Dummy, Parallel-Group Comparison of Lamotrigine and Diavalproex Sodium Monotherapy in Patients with Epilepsy Protocol SCAA4001
Glaxo Wellcome Company
Grant Years: Mar. 1997 - Ongoing
Total Grant: $53,487

Open-label Study to Evaluate the Long-Term Safety of SB204269 as Add-On Therapy in Patients with Refractory Partial Seizures Protocol 204269/009
SmithKline Beecham Pharmaeuticals
Grant Years: Apr. 1997 - Ongoing
Total Grant: $60,000

A Pilot Open-Label Evaluation of Safety, Tolerability, and Efficacy of Add-on
534U87 Treatment of Partial Seizures Protocol SCCA2001.
Glaxo Wellcome Inc.
Grant Year: May 1997 - Jun 1998
Total Grant: $35,000

Gabapentin Monotherapy Trial: A 4-Month, Double-Blind, Dose-Controlled,
parallel Group, Multicenter Study to Determine the Efficacy & Safety of
Gabapentin in New Onset Seizures Protocol 945-213.

Parke-Davis Pharmaceutical Research
Grant Years: Jun 1997 - Sept. 1998
Total Grant: $17,000

Pregabalin In-Patient Monotherapy Trial: A Double-Blind, Positive-Controlled, Multicenter Study in Patients with Refractory Partial Epilepsy Protocol 1008/007
Parke-Davis Pharmaceutical Research
Grant Years: Jun 1997 - Dec. 1998
Total Grant: $192,480

Pregabalin Open-Label, Follow-On Safety Trial in Patients with Refractory Partial Epilepsy Protocol 1008/008
Parke-Davis Pharmaceutical Research
Grant Years: Jun 1997 - Ongoing
Total Grant: $183,480

Pregabalin Add-On Trial: A Double-Blind, Placebo-Controlled, Multicenter Study in Patients with Partial Seizures Protocol 1008/009
Parke-Davis Pharmaceutical Research
Grant Years: Apr 1998 - Ongoing
Total Grant: $75,000

Pregabalin Open-Label Add-On Trial: An Open-Label, Multicenter Follow-On Study to Determine the Long-Term Safety and Efficacy in Patients with Partial Seizures Protocol 1008/010
Parke-Davis Pharmaceutical Research
Grant Years: Apr 1998 - Ongoing
Total Grant: $75,000

Topamax (Topiramate) Monotherapy Comparison Trial to Standard Monotherapy in the Treatment of Newly Diagnosed Epilepsy (TOPMAT-EPMN-105)
R.W. Johnson Pharmaceutical Research Institute
Grant Years: Apr 1998 - Ongoing
Total Grant: $27,480

Double-Blind Study Comparing the Tolerability of IM a Load Dose of Fosphenytoin Compared to IM Placebo.
Investigator initiated - Ramsay
Grant Year: Jan 1998 - Ongoing
Total Grant: $10,000 (Parke-Davis Pharmaceutical Research)

Epilepsy in the elderly: a double blind double dummy comparison of carbamazepine, gabapentin, and lamotrigine in the treatment of new onset seizures in patients 60 years and older.
National Principle investigators - R. Eugene Ramsay & A. James Rowan.
Grant Year: Jan 1998 - Dec 2002
VA Cooperative Studies Grant, 18 study centers in the US and Puerto Rico, Total Budget - $7,800,000

Multicenter, Open-Label Study of Rufinamide as Monotherapy or Adjunctive Therapy in Patients with Epileptic Seizures Protocol CRUF3310101
Novartis Pharmaceutical
Grant Year: March 1999 to Sept. 2002
Total Grant: $69,300

The Safety and Tolerance of Intravenous DepaconJ at an Infusion Rate Up to 3.0 mg/kg/minute in Subjects with Epilepsy Protocol M98-938
Abbott Laboratories
Grant Year: April 1999 to Dec. 1999
Total Grant: $55,000

Editorial responsibilities:

1987-June2000 Co-Editor, BRAIN TOPOGRAPHY: A Journal of Functional Neurophysiology, Publisher-Planum, First issue Sept. 1988
1986-present Reviewer, Neurology
1987-present Reviewer, Epilepsia
1989-present Reviewer, Epilepsy Research
1993-present Reviewer, Yearbook of Neurology and Neurosurgery
1998-present Editorial Board, Seizure disorders & Epilepsy: Index & Review

Member:

1979 American Academy of Neurology
1975 American Electroencephalographic Society
1976 American Epilepsy Society
1975 Epilepsy Foundation of Florida
1978 Epilepsy Foundation of America
1981 Southern Clinical Neurological Society
1975 Southern Electroencephalographic Society
1993 American Neurological Association

Officer:

1979-84 Laboratory Accreditation Committee, American EEG Society
1979 Hans Berger Award Committee, American EEG Society
1979-84 Joint Review Committee Site Visitor for the AMA, Accreditation of EEG Technologist Training Programs
1980-81 Chairman, Membership Committee, American Epilepsy Society
1981-present Organizer and First Chairman, Clinical Pharmacology Interest Group, American Epilepsy Society
1981-1994 Council Member, Southern Clinical Neurological Society
1981-present Clinic Medical Director of Epilepsy Foundation of South Florida
1984-85 Vice-president, Florida Epilepsy Foundation
1985-87 President, Florida Epilepsy Foundation
1984-88 Member, Professional Advisory Board, Epilepsy Foundation of America
1985-86 Chairman, Medical Student Fellowship Committee, Epilepsy Foundation of America
1986-88 Secretary/Treasurer, Southern Clinical Neurological Society
1987-88 Chairman, Brain Atlas Users Group
1988-92 Member, Professional Advisory Board, Epilepsy Foundation of America
1988-90 President, Southern Clinical Neurological Society
1988-present Member, Advocacy Committee, Epilepsy Foundation of America
1989-present Member, Laboratory Accreditation Committee, American EEG Society
1992-present Medical Director, Epilepsy Foundation of South Florida
1992-1994 Organizing Committee
Antiepileptic Drug Trials I, Miami Beach, 1993;
Antiepileptic Drug Trials II, New Orleans, 1994.
1993-1994 Co-chairman, Seizures and Epilepsy in the Elderly International Symposium, Miami, 1994.
1993-1994 Clinical Science Subcommittee, AES Investigator's Workshop, New Orleans, 1994.
1997-present American Epilepsy Society, Corporate Advisory Committe
1998-present International Epilepsy Consortium, Executive Committee

Honors and Awards:

1977-80 AMA Physician's Recognition Award in Continuing Medical Education.

1980 Incentive Award for Special Achievement, Veterans Administration Medical Center.

1980-83 AMA Physician's Recognition Award in Continuing Medical Education.

1983 Outstanding Performance Award, Veterans Administration Medical Center.

1984 Fellow, American Academy of Neurology.

1985 Outstanding Performance Award, Veterans Administration Medical Center.

1987 Medical Award from Epilepsy Foundation of South Florida.

1988 Certificate of Recognition from Barry University.

1994-98 Listed in The Best Doctors in America.

1996-98 Listed in The Best Doctors in America: Southeast Region.

1998 Member, International Who=s Who.

1998 Recipient, J. Kiffen Penry Eagle Award, Presented by Cyberonics at the American Epilepsy Society Meeting, Dec 7, 1998, San Diego
California, for work done in the development of vagal nerve
stimulation and its use in epilepsy.

CME Monographs:

Clinical Issues in the Management of Epilepsy - Medical education activity for 2 CME credit hours updates physicians on the management of patients with epilepsy with newer antiepileptic drugs. Sponsored by Burroughs Wellcome Co., 1993.

Clinical Simulations in The Diagnosis & Management of Epilepsy 2 - Medical education activity for 1 CME credit hour evaluates physicians diagnostic and medical management skills. Sponsored by Glaxo Wellcome Inc., 1997.

Epilepsy in the Elderly, 1 CME provided by the American Epilepsy Society, Sponsored by Parke-Davis. 1998

Papers Presented:

Intravenous Phenytoin. American Epilepsy Society, Biltmore Hotel, New York.

Spike and Slow Wave: A Sensitive Index of Lithium Intoxication. American Medical EEG Soc., Savannah, GA, Apr. 7, 1976.

Status Epilepticus During Pregnancy: Effects of Gastrointestinal Malabsorption on Phenytoin Kinetics and Seizure Control. American Neurological Association, Four Seasons Hotel, Toronto, Canada, Apr. 29, 1976.

Central Nervous System Penetration by Anticonvulsant Drugs. American Epilepsy Society, Nov. 1976.

Effects of Trimethadione and Ethosuximide on Bicuculline Induced Seizures. American Epilepsy Society, Nov. 1976.

Infracortical Blood: An Animal Model for Chronic Epilepsy. The Ninth International EEG and Clinical Neurophysiological Society, Amsterdam, Netherlands, Sept. 1977.

Phenytoin Pharmacokinetics During Pregnancy. 11th World Congress of Neurology, Amsterdam, Netherlands, Sept. 1977.

Electrode Anatomy. Southern EEG Soc., Chattanooga, TN, Oct. 1977.

Blood Induced Epileptogenesis: Effects of Various Blood Components. American EEG Society., San Francisco, CA, Sept. 4-9, 1978.
Plasma Clearance and Volume of Distribution of Phenytoin During Pregnancy, Epilepsy International Symposium, Vancouver, Canada, Sept. 10-14, 1978.

Twenty-four Hour Ambulatory EEG Monitoring: A Clinical Appraisal. American EEG Soc., Boston, MA, Sept. 5, 1980.

Cinromide: A Multicenter Open Study of Efficacy and Safety in Epileptic Patients with Uncontrolled Tonic-Clonic Seizures. American Epilepsy Society, San Diego, CA, Nov. 20-22, 1980.

Cinromide: Long Term Study of the Treatment of Generalized Tonic-Clonic Seizures. Pan Amer Epilepsy Soc., Merida, MX, Feb. 1981.

Clinical Usefulness of 24 Hour Ambulatory EEG Monitoring in Neurological Patients. 4th Meeting of the International Society of Ambulatory Monitoring, Gent, Belgium, June 1981.

Topographic EEG Analysis. American EEG Society, Chicago, IL, June 1981.

Carbamazepine vs. Phenytoin in the Initial Treatment of Seizures. Poster presentation; Amer Neurol Assoc., San Francisco, CA, Sept. 1981.

Topographic EEG Analysis in Focal Lesions: Comparison with PETT Scan Findings. West. EEG Soc., Seattle, WA, Mar. 29, 1982.

Regional Valproate Brain Tissue Kinetics using PETT. International Epilepsy Society, London, England, Aug. 1982.

Anticonvulsant Induced changes in Carbamazepine Metabolism. Poster presentation; American Epilepsy Society, Phoenix, AZ, Nov. 1982.

Paraldehyde Kinetics in Primates. Poster presentation; American Epilepsy Society, Phoenix, AZ, Nov. 1982.

Spike Mapping Using Topographic Display. Poster presentation; American EEG Society, Phoenix, AZ, Nov. 1982.

Valproate Brain Tissue Kinetics Determined by PETT. Poster Presentation; American Academy of Neurology, San Diego, CA, Apr. 1983.

Cerebral Metabolic Dysfunction Measured by PETT and Spectrophotometry in Active Epileptic Foci. Submitted the 15th Epilepsy International Symposium and American Epilepsy Society meeting, Washington, DC, Sept. 1983.

Controlled and Comparative Clinical Trials with Valproate: USA The 15th Epilepsy International Symposium, Washington, DC, Sept. 1983.

Changes in Hormone levels and Anticonvulsant Metabolism During Pregnancy, The 15th Epilepsy International Symposium, Washington, DC, Sept. 1983.

Oxygen Sufficiency During Seizures and in Human Epileptic Foci, The 15th Epilepsy International Symposium, Washington, DC, Sept. 1983.

Moderator, American Academy of Neurology, Dinner Session, Ambulatory EEG, Boston, MA, Apr. 1984.

Multicenter Study on the Efficacy of Zonisamide in the Treatment of Medically Refractory Complex Partial Seizures, American Epilepsy Society, San Francisco, CA, Nov. 8-9, 1984.

Acute Dose Tolerance of Wellbutrin (W), Imipramine (I), and Placebo (P) in Epileptic Patients. Poster Presentation; American Epilepsy Society, San Francisco, CA, Nov. 8-9, 1984.

"Centro-Temporal Spikes in Childhood are Not Always Indicative of a Benign Prognosis". Poster Presentation; American Epilepsy Society, San Francisco, CA, Nov. 8-9, 1984.

"Increased in Protein Binding of Carbamazepine from Danazol Co-administration". Poster Presentation; Epilepsy International, Germany, Sept. 6-9, 1985.

Placebo Effect: Fluctuation in Seizure Frequency During Placebo Treatment. American Academy of Neurology, New York, NY, Apr. 1987.

Event Related Potentials: Results of Topographic Mapping in Normal Controls and Patients Post Temporal Lobectomy. American EEG Society Annual Meeting; St. Louis, MO, Sept. 17 19, 1987.

Post-Chiasmatic Visual Pathway Defects Demonstrated by Topographic Mapping of Pattern Reversal Evoked Potentials. American EEG Society Annual Meeting; St. Louis, MO, Sept. 17 19, 1987.
Effects of Antiepileptic Drugs on Hormones. American Epilepsy Society annual meeting, San Diego, CA, Nov. 1990.

Efficacy of Vagal Nerve Stimulation in Partial Seizures. American Epilepsy Society annual meeting, Philadelphia, PA, Nov. 1991.

One-Year Follow-up of 29 Patients with Refractory Epilepsy Treated in a Controlled Study of Vagal Stimulation. American Epilepsy Society annual meeting, Seattle, WA, Dec. 1992.

Invited Outside Lectureships:

Controlled Antiepileptic Therapy. Guest lecturer on program, "Practical Approach to Pharmacokinetics and Therapeutic Drug Monitoring", sponsored by the Department of Pharmacology and Therapeutics, LSU Medical Center, Shreveport, LA, Feb. 9, 1977.

Central Nervous System Development: Normal and Abnormal. American Society of Electroencephalographic Technologists, June 1977.

Effects of Pregnancy on Epilepsy. Epilepsy International Symposium, Vancouver, Canada, Sept. 10-14, 1978.

Epileptic complications of Pregnancy, Epilepsy Seminar, Kingston, Jamaica, Nov. 18, 1979.

New Advances in Anticonvulsant. Epilepsy Seminar, Kingston, Jamaica, Nov. 19, 1979.

Recent Developments in Evoked Potentials. Southern Clinical Neurological Society, Curacao, Jan. 30, 1980.

Positron Emission Tomography. Michigan Society for Neurosciences, May 1981.

Moderator, Morning Session on Ambulatory EEG Monitoring, Fourth meeting of International Society for Ambulatory Monitoring. Gent, Belgium, June 1981.

Medical Management of seizures. Epilepsy seminar, Southern EEG Society, Oct. 1981.

Member, Ciba-Geigy Speakers Bureau
Member, Abbott Speakers Bureau

Controlled and Comparison Clinical Trials with Valproate: USA. The 15th Epilepsy International Symposium; Washington, DC, Sept. 1983.

Changes in Hormone Levels and Anticonvulsant Metabolism During Pregnancy, The 15th Epilepsy International Symposium; Washington, DC, Sept. 1983.

Member, Merritt Putnam Speakers Bureau

Brain Metabolism and Positron Emission Tomography; invited to present to the Southern Clinical Neurological Society, Ocho Rios, Jamaica, Jan. 24, 1984.

Evidence for EEG Source Generators from PET Data; invited to present to the International Federation of Electroencephalography, London, England, Aug. 25-30, 1984.

Use of Stable Isotopes in Evaluating Pharmacokinetic Parameters in Pregnancy invited to present to the Symposium on Stable Isotope, Philadelphia, PA, Feb. 1985.

Antiepileptic Drugs In Pregnancy; invited to present to the Ciba-Geigy Pharmaceutical Symposium, St. Thomas, U.S. Virgin Islands, Jan. 5-9, 1985.

Epilepsy and Pregnancy; Sponsored by The Epilepsy Symposium, University of Kentucky, Nov. 1985.

Topographic Mapping; Presented to American EEG Society; Special Course, New York, NY, Dec. 2, 1985.

Southern EEG Society Annual Meeting; Charleston, SC, Mar. 20-22, 1986.

Hans Berger EEG Symposium; Digital EEG and Tonic-Clonic Seizures. Richmond, VA, May 19 20, 1986.

Symposium at the American Academy of Neurology, A Decade of Valproate; Title of presentation - The Use of Valproic Acid in the Treatment of Primary Generalized Seizures. Cincinnati, OH, Apr. 1988.

Conversion from Polytherapy to Valproate Monotherapy in Patients with Uncontrolled Primary Generalized Convulsive Seizures. Am Epilepsy Society, San Francisco, CA, Oct. 1988.

Symposium at the American Epilepsy Society, Parental Drugs in the Treatment of Status Epilepticus; Title of presentation - Pharmacokinetics and Tissue Kinetics of Phenytoin, Phenobarbital, and Paraldehyde, San Francisco, CA, Sept. 1988.

Use of Computerized EEG in the Evaluation of Patients with Epilepsy. American Soc EEG Technologists, New Orleans, LA, Sept. 1989.

Symposium at the American Epilepsy Society meeting sponsored by Neurology Nurses Association; Title of Presentation - Safety and Systemic Effects of Vagal Stimulations, Boston, MA, Dec. 1989.

NIH sponsored conference on non-epileptic seizures. Title: "The Concurrent Existence of Epilepsy and Non-Epileptic Seizures", Ft. Lauderdale, FL, Feb. 1990.

International Symposium on Epilepsy and Teratogenesis, Los Angeles, CA, July 1990.

Update on Teratogenesis of AEDs, Bowman-Gray Mini-fellowship Conference, AES, San Diego, CA, Nov. 1990.

Lecture series on vagal stimulation to neurosurgeons and neurologists at Tokyo Metropolitan Neurology Hospital and at the annual meeting of the Japanese Society for Electrical Stimulation Therapy, Tokyo, Japan, Oct. 1991.

Antiepileptic Drug Trials I: Investigator's Workshop, sponsored by The Graduate Hospital, Miami Beach, FL, Mar. 1992.

New Anticonvulsants in Development, Bowman-Gray MiniFellowship. American Epilepsy Society annual meeting, Seattle, WA, Dec. 1992.

Antiepileptic Drug Trials II: Investigator's Workshop, Sponsored by The Graduate Hospital, New Orleans, LA, Mar. 1994.

Fosphenytoin in the treatment of acute seizures and status epilepticus. European epilepsy Congress, Jun 1998, Nice, France


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